|
 Gene description for AQP5 |
| Gene name |
aquaporin 5 |
| Gene symbol |
AQP5 |
| Other names/aliases |
AQP-5
PPKB |
| Species |
Homo sapiens |
| Database cross references - AQP5 |
| ExoCarta |
ExoCarta_362 |
| Vesiclepedia |
VP_362 |
| Entrez Gene |
362 |
| HGNC |
638 |
| MIM |
600442 |
| UniProt |
P55064
|
| AQP5 identified in exosomes derived from the following tissue/cell type |
|
Ovarian cancer cells
|
23333927
|
|
Ovarian cancer cells
|
23333927
|
|
Saliva
|
19199708
|
| Gene ontology annotations for AQP5 |
|
|
| Experiment description of studies that identified AQP5 in exosomes |
| 1 |
| Experiment ID |
211 |
| MISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✔
TSG101|Alix|EpCAM|TFRC
|
EV Enriched markers |
|
✔
cytochrome c|GOLGA2
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
23333927
|
| Organism |
Homo sapiens |
| Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
| Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
| Journal name |
J Proteomics
|
| Publication year |
2013 |
| Sample |
Ovarian cancer cells |
| Sample name |
IGROV1 |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.09-1.15 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 2 |
| Experiment ID |
212 |
| MISEV standards |
|
✔
CEM
|
EV Biophysical techniques |
|
✔
TSG101|Alix|EpCAM|TFRC
|
EV Enriched markers |
|
✔
Cytochrome C|GOLGA2
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
23333927
|
| Organism |
Homo sapiens |
| Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
| Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
| Journal name |
J Proteomics
|
| Publication year |
2013 |
| Sample |
Ovarian cancer cells |
| Sample name |
OVCAR-3 |
| Isolation/purification methods |
Differential centrifugation
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.09-1.15 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| 3 |
| Experiment ID |
66 |
| MISEV standards |
|
✔
IEM
|
EV Biophysical techniques |
|
✔
TSG101|Alix|CD63|CD81
|
EV Enriched markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
Western blotting
|
| PubMed ID |
19199708
|
| Organism |
Homo sapiens |
| Experiment description |
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). |
| Authors |
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR |
| Journal name |
JPR
|
| Publication year |
2009 |
| Sample |
Saliva |
| Sample name |
Saliva |
| Isolation/purification methods |
Differential centrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy |
|
|
| Protein-protein interactions for AQP5 |
|
|
| Pathways in which AQP5 is involved |
|
|
|
