Gene description for IRF6
Gene name	interferon regulatory factor 6
Gene symbol	IRF6
Other names/aliases	LPS OFC6 PIT PPS PPS1 VWS VWS1
Species	Homo sapiens
Database cross references - IRF6
ExoCarta	ExoCarta_3664
Vesiclepedia	VP_3664
Entrez Gene	3664
HGNC	6121
MIM	607199
UniProt	O14896
IRF6 identified in exosomes derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for IRF6

Molecular Function     protein binding GO:0005515 IPI     DNA binding GO:0003677 ISS     regulatory region DNA binding GO:0000975 IEA     sequence-specific DNA binding transcription factor activity GO:0003700 ISS Biological Process     keratinocyte proliferation GO:0043616 IEA     transcription, DNA-templated GO:0006351 IEA     interferon-gamma-mediated signaling pathway GO:0060333 TAS     mammary gland epithelial cell differentiation GO:0060644 ISS     cell development GO:0048468 IEA     negative regulation of cell proliferation GO:0008285 IDA     cell cycle arrest GO:0007050 IDA     type I interferon signaling pathway GO:0060337 TAS     keratinocyte differentiation GO:0030216 IEA     cytokine-mediated signaling pathway GO:0019221 TAS     positive regulation of transcription, DNA-templated GO:0045893 ISS Subcellular Localization     cytoplasm GO:0005737 IDA     extracellular exosome GO:0070062 IDA     nucleus GO:0005634 IEA     cytosol GO:0005829 TAS