Gene description for AP5M1
Gene name adaptor-related protein complex 5, mu 1 subunit
Gene symbol AP5M1
Other names/aliases C14orf108
MUDENG
Mu5
MuD
Species Homo sapiens
 Database cross references - AP5M1
ExoCarta ExoCarta_55745
Entrez Gene 55745
HGNC 20192
MIM 614368
UniProt Q9H0R1  
 AP5M1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for AP5M1
Biological Process
    endosomal transport GO:0016197 IMP
    intracellular protein transport GO:0006886 IEA
    vesicle-mediated transport GO:0016192 IEA
Subcellular Localization
    clathrin adaptor complex GO:0030131 IEA
    cytosol GO:0005829 IDA
    membrane GO:0016020 IDA
    late endosome membrane GO:0031902 IEA
    lysosome GO:0005764 IDA
    late endosome GO:0005770 IDA
    lysosomal membrane GO:0005765 IEA
    AP-type membrane coat adaptor complex GO:0030119 IDA
 Experiment description of studies that identified AP5M1 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for AP5M1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which AP5M1 is involved
No pathways found





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