Gene description for RN7SL1
Gene name RNA, 7SL, cytoplasmic 1
Gene symbol RN7SL1
Other names/aliases 7L1a
7SL
RN7SL
RNSRP1
Species Homo sapiens
 Database cross references - RN7SL1
ExoCarta ExoCarta_6029
Vesiclepedia VP_6029
Entrez Gene 6029
HGNC 10038
MIM 612177
 RN7SL1 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for RN7SL1
Biological Process
    SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition GO:0006617 IEA
Subcellular Localization
    signal recognition particle, endoplasmic reticulum targeting GO:0005786 IEA
 Experiment description of studies that identified RN7SL1 in exosomes
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule ncRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for RN7SL1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GEMIN6  
Protein-RNA Homo sapiens
2 GEMIN5 25929
Affinity Capture-RNA Homo sapiens
Protein-RNA Homo sapiens
3 GEMIN8 54960
Protein-RNA Homo sapiens
4 GEMIN4 50628
Protein-RNA Homo sapiens
5 GEMIN7  
Protein-RNA Homo sapiens
6 DDX20 11218
Protein-RNA Homo sapiens
7 SMN1 6606
Affinity Capture-RNA Homo sapiens
Protein-RNA Homo sapiens
8 GEMIN2 8487
Affinity Capture-RNA Homo sapiens
Protein-RNA Homo sapiens
9 STRAP 11171
Protein-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which RN7SL1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here