Gene description for ALDH8A1
Gene name aldehyde dehydrogenase 8 family, member A1
Gene symbol ALDH8A1
Other names/aliases ALDH12
DJ352A20.2
Species Homo sapiens
 Database cross references - ALDH8A1
ExoCarta ExoCarta_64577
Entrez Gene 64577
HGNC 15471
MIM 606467
UniProt Q9H2A2  
 ALDH8A1 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for ALDH8A1
Molecular Function
    aldehyde dehydrogenase (NAD) activity GO:0004029 IBA
    retinal dehydrogenase activity GO:0001758 IDA
Biological Process
    9-cis-retinoic acid biosynthetic process GO:0042904 IEA
    retinal metabolic process GO:0042574 IDA
    retinoic acid metabolic process GO:0042573 IDA
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    intracellular GO:0005622 IDA
    extracellular exosome GO:0070062 IDA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified ALDH8A1 in exosomes
1
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
AQP2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ALDH8A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ALDH8A1 is involved
No pathways found





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