Gene description for Rras2
Gene name related RAS viral (r-ras) oncogene homolog 2
Gene symbol Rras2
Other names/aliases 2610016H24Rik
C86394
TC21
Species Mus musculus
 Database cross references - Rras2
ExoCarta ExoCarta_66922
Entrez Gene 66922
UniProt P62071  
 Rras2 identified in exosomes derived from the following tissue/cell type
Embryonic fibroblasts 18494037    
 Gene ontology annotations for Rras2
Molecular Function
    GTP binding GO:0005525 IEA
    protein binding GO:0005515 IPI
    nucleotide binding GO:0000166 IEA
Biological Process
    signal transduction GO:0007165 IEA
    Ras protein signal transduction GO:0007265 IDA
    positive regulation of cell migration GO:0030335 IGI
    regulation of neuron death GO:1901214 ISO
    cellular process GO:0009987 IPI
    osteoblast differentiation GO:0001649 ISO
    small GTPase mediated signal transduction GO:0007264 IEA
Subcellular Localization
    extracellular exosome GO:0070062 ISO
    focal adhesion GO:0005925 ISO
    membrane GO:0016020 ISO
    intracellular GO:0005622 IDA
    plasma membrane GO:0005886 IEA
 Experiment description of studies that identified Rras2 in exosomes
1
Experiment ID 73
ISEV standards
EM
EV Biophysical techniques
HSP70|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 18494037    
Organism Mus musculus
Experiment description Difference gel electrophoresis analysis of Ras-transformed fibroblast cell-derived exosomes.
Authors Ji H, Erfani N, Tauro BJ, Kapp EA, Zhu HJ, Moritz RL, Lim JW, Simpson RJ
Journal name ELEC
Publication year 2008
Sample Embryonic fibroblasts
Sample name NIH3T3
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA]
Western blotting
 Protein-protein interactions for Rras2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SMURF2  
Affinity Capture-Luminescence Homo sapiens
2 SMAD3  
Affinity Capture-Luminescence Homo sapiens
3 ACVR1 90
Affinity Capture-Luminescence Homo sapiens
4 SMAD4  
Affinity Capture-Luminescence Homo sapiens
5 BMPR1B  
Affinity Capture-Luminescence Homo sapiens
View the network image/svg+xml
 Pathways in which Rras2 is involved
No pathways found





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