Gene description for VEPH1
Gene name ventricular zone expressed PH domain-containing 1
Gene symbol VEPH1
Other names/aliases MELT
VEPH
Species Homo sapiens
 Database cross references - VEPH1
ExoCarta ExoCarta_79674
Vesiclepedia VP_79674
Entrez Gene 79674
HGNC 25735
MIM 609594
UniProt Q14D04  
 VEPH1 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for VEPH1
Molecular Function
    protein binding GO:0005515 IPI
    phosphatidylinositol-5-phosphate binding GO:0010314 IBA
Biological Process
    regulation of signal transduction GO:0009966 IBA
    negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 IDA
    negative regulation of SMAD protein signal transduction GO:0060392 IDA
Subcellular Localization
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified VEPH1 in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for VEPH1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TOP3B 8940
Affinity Capture-MS Homo sapiens
2 TUBA4A 7277
Affinity Capture-MS Homo sapiens
3 TNFAIP3 7128
Affinity Capture-MS Homo sapiens
4 DLG5 9231
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which VEPH1 is involved
No pathways found





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