Gene description for SLC10A3
Gene name solute carrier family 10, member 3
Gene symbol SLC10A3
Other names/aliases DXS253E
P3
Species Homo sapiens
 Database cross references - SLC10A3
ExoCarta ExoCarta_8273
Entrez Gene 8273
HGNC 22979
MIM 312090
UniProt P09131  
 SLC10A3 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for SLC10A3
Molecular Function
    bile acid:sodium symporter activity GO:0008508 IBA
Biological Process
    transmembrane transport GO:0055085 IEA
    response to retinoic acid GO:0032526 IEA
    bile acid and bile salt transport GO:0015721 IBA
Subcellular Localization
    integral component of plasma membrane GO:0005887 IBA
 Experiment description of studies that identified SLC10A3 in exosomes
1
Experiment ID 235
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for SLC10A3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SLC10A3 is involved
No pathways found





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