Gene description for Clta
Gene name clathrin, light chain A
Gene symbol Clta
Other names/aliases LCA1
LCA2
LCA3
Species Rattus norvegicus
 Database cross references - Clta
ExoCarta ExoCarta_83800
Entrez Gene 83800
UniProt P08081  
 Clta identified in exosomes derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Clta
Molecular Function
    structural molecule activity GO:0005198 IBA
    clathrin heavy chain binding GO:0032050 ISO
    protein binding GO:0005515 IPI
    peptide binding GO:0042277 IDA
Biological Process
    clathrin-mediated endocytosis GO:0072583 IBA
    endocytosis GO:0006897 IEP
    intracellular protein transport GO:0006886 IEA
Subcellular Localization
    clathrin coat of coated pit GO:0030132 NAS
    coated pit GO:0005905 IDA
    clathrin-coated vesicle GO:0030136 IDA
    clathrin coat GO:0030118 IDA
    cytoplasmic membrane-bounded vesicle GO:0016023 ISO
    clathrin complex GO:0071439 ISO
    clathrin vesicle coat GO:0030125 NAS
    membrane GO:0016020 ISO
    clathrin coat of trans-Golgi network vesicle GO:0030130 IEA
    clathrin-coated endocytic vesicle membrane GO:0030669 TAS
    intracellular membrane-bounded organelle GO:0043231 ISO
 Experiment description of studies that identified Clta in exosomes
1
Experiment ID 35
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
CD81|CD63
EV Membrane markers
HSPA5
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Clta
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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