Experiment description of studies that identified C9orf3 in exosomes

1 Experiment ID 226 MISEV standards ✔ EM Biophysical techniques ✔ GAPDH|CD9|FLOT1 Enriched markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 Negative markers ✘ Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting" Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar" Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

Protein-protein interactions for C9orf3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 C15orf39   Affinity Capture-MS Homo sapiens 2 ZDHHC17 23390 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 TUBA4A 7277 Affinity Capture-MS Homo sapiens 4 TUBB3 10381 Affinity Capture-MS Homo sapiens 5 LRRC40 55631 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 ZBTB39   Affinity Capture-MS Homo sapiens 7 SUN2 25777 Co-crystal Structure Homo sapiens 8 SUZ12   Affinity Capture-MS Homo sapiens View the network

Pathways in which C9orf3 is involved

No pathways found