Gene description for MYOM2
Gene name myomesin 2
Gene symbol MYOM2
Other names/aliases TTNAP
Species Homo sapiens
 Database cross references - MYOM2
ExoCarta ExoCarta_9172
Vesiclepedia VP_9172
Entrez Gene 9172
HGNC 7614
MIM 603509
UniProt P54296  
 MYOM2 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for MYOM2
Molecular Function
    protein binding GO:0005515 IPI
    structural constituent of muscle GO:0008307 TAS
    kinase binding GO:0019900 IPI
Biological Process
    extraocular skeletal muscle development GO:0002074 IEA
    muscle contraction GO:0006936 TAS
    sarcomere organization GO:0045214 IBA
    sarcomere organization GO:0045214 IMP
Subcellular Localization
    mitochondrion GO:0005739 HDA
    M band GO:0031430 IBA
    myosin filament GO:0032982 IEA
 Experiment description of studies that identified MYOM2 in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MYOM2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LATS1  
Affinity Capture-MS Homo sapiens
2 AURKB 9212
Affinity Capture-MS Homo sapiens
3 RSPH6A  
Affinity Capture-MS Homo sapiens
4 TERF2  
Affinity Capture-MS Homo sapiens
5 HSPB2  
Two-hybrid Homo sapiens
6 TSPAN33 340348
Affinity Capture-MS Homo sapiens
7 EHMT2 10919
Affinity Capture-MS Homo sapiens
8 C1QTNF7  
Affinity Capture-MS Homo sapiens
9 CIT 11113
Affinity Capture-MS Homo sapiens
10 HSP90B1 7184
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which MYOM2 is involved
No pathways found





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