Gene description for CD101
Gene name CD101 molecule
Gene symbol CD101
Other names/aliases EWI-101
IGSF2
V7
Species Homo sapiens
 Database cross references - CD101
ExoCarta ExoCarta_9398
Vesiclepedia VP_9398
Entrez Gene 9398
HGNC 5949
MIM 604516
UniProt Q93033  
 CD101 identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
 Gene ontology annotations for CD101
Molecular Function
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides GO:0016812 IEA
Biological Process
    positive regulation of myeloid leukocyte differentiation GO:0002763 IEA
    cell surface receptor signaling pathway GO:0007166 TAS
Subcellular Localization
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 IBA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified CD101 in sEVs
1
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
 Protein-protein interactions for CD101
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SRSF5 6430
Two-hybrid Homo sapiens
2 ST13 6767
Two-hybrid Homo sapiens
3 DDX58 23586
Affinity Capture-RNA Homo sapiens
4 FBXO2 26232
Affinity Capture-MS Homo sapiens
5 SH3GL3  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which CD101 is involved
PathwayEvidenceSource
Adaptive Immune System TAS Reactome
Generation of second messenger molecules TAS Reactome
Immune System TAS Reactome
TCR signaling TAS Reactome





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