Gene description for GMFG
Gene name glia maturation factor, gamma
Gene symbol GMFG
Other names/aliases GMF-GAMMA
Species Homo sapiens
 Database cross references - GMFG
ExoCarta ExoCarta_9535
Entrez Gene 9535
HGNC 4374
MIM 604104
UniProt O60234  
 GMFG identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for GMFG
Molecular Function
    Arp2/3 complex binding GO:0071933 IEA
    growth factor activity GO:0008083 IEA
    protein kinase inhibitor activity GO:0004860 TAS
    actin binding GO:0003779 IEA
    enzyme activator activity GO:0008047 TAS
Biological Process
    negative regulation of protein kinase activity GO:0006469 TAS
    protein phosphorylation GO:0006468 TAS
    regulation of actin cytoskeleton reorganization GO:2000249 IEA
    negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316 IEA
    positive regulation of catalytic activity GO:0043085 TAS
Subcellular Localization
    intracellular GO:0005622 IEA
 Experiment description of studies that identified GMFG in exosomes
1
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GMFG
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GMFG is involved
No pathways found





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