Gene description for HIST2H3PS2
Gene name histone cluster 2, H3, pseudogene 2
Gene symbol HIST2H3PS2
Other names/aliases p06
Species Homo sapiens
 Database cross references - HIST2H3PS2
ExoCarta ExoCarta_440686
Vesiclepedia VP_440686
Entrez Gene 440686
HGNC 32060
 HIST2H3PS2 identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for HIST2H3PS2
Molecular Function
    DNA binding GO:0003677 IEA
    structural constituent of chromatin GO:0030527 IEA
    protein heterodimerization activity GO:0046982 IEA
Subcellular Localization
    nucleosome GO:0000786 IEA
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified HIST2H3PS2 in sEVs
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for HIST2H3PS2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HSD3B2 3284
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 HIST1H4K 8362
Affinity Capture-MS Homo sapiens
3 HIST1H2BE 8344
Affinity Capture-MS Homo sapiens
4 MACROD1 28992
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 AIPL1  
Affinity Capture-MS Homo sapiens
6 SRFBP1  
Affinity Capture-MS Homo sapiens
7 CENPA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 GOLGA7 51125
Affinity Capture-MS Homo sapiens
9 ANXA9  
Affinity Capture-MS Homo sapiens
10 WDR76  
Affinity Capture-MS Homo sapiens
11 MCM2 4171
Affinity Capture-MS Homo sapiens
12 ELOVL1 64834
Affinity Capture-MS Homo sapiens
13 SUV39H1  
Affinity Capture-MS Homo sapiens
14 TMEM184B  
Affinity Capture-MS Homo sapiens
15 H2AFY2 55506
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 RTN1 6252
Affinity Capture-MS Homo sapiens
17 HMGA2 8091
Affinity Capture-MS Homo sapiens
18 HIST2H2AC 8338
Affinity Capture-MS Homo sapiens
19 PHF11 51131
Affinity Capture-MS Homo sapiens
20 KLHL20  
Affinity Capture-MS Homo sapiens
21 RAB39B 116442
Affinity Capture-MS Homo sapiens
22 C18orf21  
Affinity Capture-MS Homo sapiens
23 RRP7A 27341
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 HSPA8 3312
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 PPM1B 5495
Affinity Capture-MS Homo sapiens
26 FOXE3  
Affinity Capture-MS Homo sapiens
27 LACC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 HIST1H3C 8352
Affinity Capture-MS Homo sapiens
29 P2RY8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 LAIR1  
Affinity Capture-MS Homo sapiens
31 SLC6A20  
Affinity Capture-MS Homo sapiens
32 HIST1H2AM 8336
Affinity Capture-MS Homo sapiens
33 HIST1H3J 8356
Affinity Capture-MS Homo sapiens
34 HIST1H3B 8358
Affinity Capture-MS Homo sapiens
35 HMGN1  
Affinity Capture-MS Homo sapiens
36 SARAF  
Affinity Capture-MS Homo sapiens
37 PIGT 51604
Affinity Capture-MS Homo sapiens
38 IQUB  
Affinity Capture-MS Homo sapiens
39 SSUH2  
Affinity Capture-MS Homo sapiens
40 CENPQ  
Affinity Capture-MS Homo sapiens
41 HCN1  
Affinity Capture-MS Homo sapiens
42 CDX1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 TSSK4 283629
Affinity Capture-MS Homo sapiens
44 HIST1H3F 8968
Affinity Capture-MS Homo sapiens
45 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
46 HIST1H3A 8350
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 FANCD2  
Affinity Capture-MS Homo sapiens
48 NASP 4678
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 AGPAT1 10554
Affinity Capture-MS Homo sapiens
50 CCNYL1 151195
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 ZC3HC1  
Affinity Capture-MS Homo sapiens
52 COX6B1 1340
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 H3F3B 3021
Affinity Capture-MS Homo sapiens
54 PLD5  
Affinity Capture-MS Homo sapiens
55 EMX2  
Affinity Capture-MS Homo sapiens
56 SDC2 6383
Affinity Capture-MS Homo sapiens
57 C12orf65  
Affinity Capture-MS Homo sapiens
58 CBX6  
Affinity Capture-MS Homo sapiens
59 C1orf174  
Affinity Capture-MS Homo sapiens
60 HIST1H2BA 255626
Affinity Capture-MS Homo sapiens
61 HIST1H4F 8361
Affinity Capture-MS Homo sapiens
62 HIST1H3I 8354
Affinity Capture-MS Homo sapiens
63 HIST1H4I 8294
Affinity Capture-MS Homo sapiens
64 SGOL2 151246
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 APLF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 STX17 55014
Affinity Capture-MS Homo sapiens
67 TOMM20 9804
Affinity Capture-MS Homo sapiens
68 URM1  
Affinity Capture-MS Homo sapiens
69 H2AFX 3014
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 CXorf66  
Affinity Capture-MS Homo sapiens
71 ZNF428  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 SIRT6  
Affinity Capture-MS Homo sapiens
73 HMGN4  
Affinity Capture-MS Homo sapiens
74 SSH1  
Affinity Capture-MS Homo sapiens
75 DRD3  
Affinity Capture-MS Homo sapiens
76 MCM5 4174
Affinity Capture-MS Homo sapiens
77 CDK15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 PTDSS1 9791
Affinity Capture-MS Homo sapiens
79 H2AFB3  
Affinity Capture-MS Homo sapiens
80 MBNL1 4154
Affinity Capture-MS Homo sapiens
81 HDGFRP2 84717
Affinity Capture-MS Homo sapiens
82 E2F4  
Affinity Capture-MS Homo sapiens
83 HIST1H4L 8368
Affinity Capture-MS Homo sapiens
84 TECTB  
Affinity Capture-MS Homo sapiens
85 GOT1 2805
Affinity Capture-MS Homo sapiens
86 HERC3 8916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 DUSP4 1846
Affinity Capture-MS Homo sapiens
88 CCR1  
Affinity Capture-MS Homo sapiens
89 GUCY1A3  
Affinity Capture-MS Homo sapiens
90 HIST1H2AE 3012
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which HIST2H3PS2 is involved
No pathways found





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