Gene description for SERPINB3
Gene name serpin peptidase inhibitor, clade B (ovalbumin), member 3
Gene symbol SERPINB3
Other names/aliases HsT1196
SCC
SCCA-1
SCCA-PD
SCCA1
T4-A
Species Homo sapiens
 Database cross references - SERPINB3
ExoCarta ExoCarta_6317
Vesiclepedia VP_6317
Entrez Gene 6317
HGNC 10569
MIM 600517
UniProt P29508  
 SERPINB3 identified in sEVs derived from the following tissue/cell type
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Tracheobronchial cells 19190083    
Urine 19056867    
 Gene ontology annotations for SERPINB3
Molecular Function
    virus receptor activity GO:0001618 IDA
    protease binding GO:0002020 IPI
    serine-type endopeptidase inhibitor activity GO:0004867 IBA
    serine-type endopeptidase inhibitor activity GO:0004867 NAS
    cysteine-type endopeptidase inhibitor activity GO:0004869 IMP
    protein binding GO:0005515 IPI
Biological Process
    positive regulation of cell population proliferation GO:0008284 IMP
    negative regulation of peptidase activity GO:0010466 IDA
    positive regulation of epithelial to mesenchymal transition GO:0010718 IMP
    positive regulation of endopeptidase activity GO:0010950 IDA
    negative regulation of endopeptidase activity GO:0010951 IBA
    negative regulation of endopeptidase activity GO:0010951 IMP
    positive regulation of cell migration GO:0030335 IMP
    autocrine signaling GO:0035425 IMP
    paracrine signaling GO:0038001 IMP
    negative regulation of catalytic activity GO:0043086 IDA
    negative regulation of JUN kinase activity GO:0043508 IMP
    negative regulation of proteolysis GO:0045861 IDA
    symbiont entry into host cell GO:0046718 IEA
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IBA
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    plasma membrane GO:0005886 IDA
    cytoplasmic vesicle GO:0031410 IDA
    vesicle GO:0031982 HDA
    azurophil granule lumen GO:0035578 TAS
    extracellular exosome GO:0070062 HDA
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified SERPINB3 in sEVs
1
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
6
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
11
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 34
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
TSG101|CD63|MHCI|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19190083    
Organism Homo sapiens
Experiment description Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.
Authors "Kesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK"
Journal name FASEB
Publication year 2009
Sample Tracheobronchial cells
Sample name Tracheobronchial epithelial cells
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density 1.16 -1.18 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
FACS
17
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for SERPINB3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC37A4 2542
Affinity Capture-MS Homo sapiens
2 BPHL 670
Affinity Capture-MS Homo sapiens
3 FMOD 2331
Affinity Capture-MS Homo sapiens
4 SERPINB4 6318
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 SKI 6497
Affinity Capture-MS Homo sapiens
6 RPS19BP1  
Affinity Capture-MS Homo sapiens
7 RTCA 8634
Affinity Capture-MS Homo sapiens
8 MARCH2  
Affinity Capture-MS Homo sapiens
9 EBF2  
Affinity Capture-MS Homo sapiens
10 ZIC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 TRIM55  
Affinity Capture-MS Homo sapiens
12 RPS2P32  
Affinity Capture-MS Homo sapiens
13 JADE1  
Affinity Capture-MS Homo sapiens
14 PLAC8L1  
Affinity Capture-MS Homo sapiens
15 ST7  
Affinity Capture-MS Homo sapiens
16 CASP14 23581
Affinity Capture-MS Homo sapiens
17 FNDC5  
Affinity Capture-MS Homo sapiens
18 COPS5 10987
Affinity Capture-MS Homo sapiens
19 DPPA4  
Affinity Capture-MS Homo sapiens
20 B3GNT2 10678
Affinity Capture-MS Homo sapiens
21 MCM2 4171
Affinity Capture-MS Homo sapiens
22 GRK4  
Affinity Capture-MS Homo sapiens
23 NUDT3 11165
Affinity Capture-MS Homo sapiens
24 OR13C3  
Affinity Capture-MS Homo sapiens
25 UGT1A10  
Affinity Capture-MS Homo sapiens
26 USF2 7392
Affinity Capture-MS Homo sapiens
27 MRPL39 54148
Affinity Capture-MS Homo sapiens
28 PHF11 51131
Affinity Capture-MS Homo sapiens
29 SFN 2810
Affinity Capture-MS Homo sapiens
30 ZSCAN20  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 KLHL11  
Affinity Capture-MS Homo sapiens
32 AGPAT1 10554
Affinity Capture-MS Homo sapiens
33 C18orf21  
Affinity Capture-MS Homo sapiens
34 C11orf54 28970
Co-fractionation Homo sapiens
35 DDX19B 11269
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 ZYX 7791
Affinity Capture-MS Homo sapiens
37 NF2 4771
Affinity Capture-MS Homo sapiens
38 ZNF550  
Affinity Capture-MS Homo sapiens
39 DDX31  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 POF1B 79983
Affinity Capture-MS Homo sapiens
41 RNF4 6047
Affinity Capture-MS Homo sapiens
42 ST6GALNAC6 30815
Affinity Capture-MS Homo sapiens
43 LRRC10  
Affinity Capture-MS Homo sapiens
44 FUNDC2 65991
Affinity Capture-MS Homo sapiens
45 CERS3  
Affinity Capture-MS Homo sapiens
46 RNF115  
Affinity Capture-MS Homo sapiens
47 ARHGEF40 55701
Affinity Capture-MS Homo sapiens
48 SRRT 51593
Affinity Capture-MS Homo sapiens
49 ASCL1  
Affinity Capture-MS Homo sapiens
50 RASSF9  
Affinity Capture-MS Homo sapiens
51 SFMBT1 51460
Affinity Capture-MS Homo sapiens
52 FANCG 2189
Affinity Capture-MS Homo sapiens
53 ITLN2  
Affinity Capture-MS Homo sapiens
54 COQ5  
Affinity Capture-MS Homo sapiens
55 TRIM21 6737
Affinity Capture-MS Homo sapiens
56 SARAF  
Affinity Capture-MS Homo sapiens
57 PIGT 51604
Affinity Capture-MS Homo sapiens
58 TPI1 7167
Co-fractionation Homo sapiens
59 SLC25A32 81034
Affinity Capture-MS Homo sapiens
60 S100A8 6279
Affinity Capture-MS Homo sapiens
61 SSUH2  
Affinity Capture-MS Homo sapiens
62 HCN1  
Affinity Capture-MS Homo sapiens
63 CUL2 8453
Affinity Capture-MS Homo sapiens
64 UPK1A 11045
Affinity Capture-MS Homo sapiens
65 DDX39B 7919
Affinity Capture-MS Homo sapiens
66 SCN3B  
Affinity Capture-MS Homo sapiens
67 UCHL5 51377
Reconstituted Complex Homo sapiens
68 CYLD  
Affinity Capture-MS Homo sapiens
69 DKK2  
Affinity Capture-MS Homo sapiens
70 CTSK 1513
Reconstituted Complex Homo sapiens
71 FOXH1  
Affinity Capture-MS Homo sapiens
72 MRM1  
Affinity Capture-MS Homo sapiens
73 RHBDD1 84236
Affinity Capture-MS Homo sapiens
74 PSMA3 5684
Affinity Capture-MS Homo sapiens
75 PCP4  
Affinity Capture-MS Homo sapiens
76 PPP2R2B 5521
Affinity Capture-MS Homo sapiens
77 IVL 3713
Affinity Capture-MS Homo sapiens
78 NDST2  
Affinity Capture-MS Homo sapiens
79 FANCD2  
Affinity Capture-MS Homo sapiens
80 AIFM1 9131
Affinity Capture-MS Homo sapiens
81 CCNC  
Affinity Capture-MS Homo sapiens
82 ZFPL1 7542
Affinity Capture-MS Homo sapiens
83 S100A7 6278
Affinity Capture-MS Homo sapiens
84 C16orf70  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 ASCC1 51008
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 FAM60A  
Affinity Capture-MS Homo sapiens
87 TBC1D22B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 RAB11A 8766
Affinity Capture-MS Homo sapiens
89 NPTN 27020
Affinity Capture-MS Homo sapiens
90 MOGAT3  
Affinity Capture-MS Homo sapiens
91 CD274 29126
Affinity Capture-MS Homo sapiens
92 UCP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
94 PKD2L2 27039
Affinity Capture-MS Homo sapiens
95 NPPA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 PDIA3 2923
Affinity Capture-MS Homo sapiens
97 FTH1 2495
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 LGALS7 3963
Affinity Capture-MS Homo sapiens
99 CREM  
Affinity Capture-MS Homo sapiens
100 SUSD3 203328
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 C21orf59 56683
Affinity Capture-MS Homo sapiens
102 HES4  
Affinity Capture-MS Homo sapiens
103 CTSD 1509
Affinity Capture-MS Homo sapiens
104 RASSF10  
Affinity Capture-MS Homo sapiens
105 PDE4DIP 9659
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 COA5  
Affinity Capture-MS Homo sapiens
107 BLMH 642
Affinity Capture-MS Homo sapiens
108 CTSS 1520
Reconstituted Complex Homo sapiens
109 EEF1A2 1917
Affinity Capture-MS Homo sapiens
110 ACAD9 28976
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 HDLBP 3069
Affinity Capture-MS Homo sapiens
112 CTSL 1514
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
113 EIF2B1 1967
Co-fractionation Homo sapiens
114 SLC25A6 293
Affinity Capture-MS Homo sapiens
115 AZGP1 563
Affinity Capture-MS Homo sapiens
116 MRPL38  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
117 FCRL5  
Affinity Capture-MS Homo sapiens
118 RASSF7  
Affinity Capture-MS Homo sapiens
119 STX17 55014
Affinity Capture-MS Homo sapiens
120 RIPPLY3  
Affinity Capture-MS Homo sapiens
121 UBE2U  
Affinity Capture-MS Homo sapiens
122 SERPINB5 5268
Affinity Capture-MS Homo sapiens
123 PRSS16 10279
Affinity Capture-MS Homo sapiens
124 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
125 FASN 2194
Positive Genetic Homo sapiens
126 FAM153B  
Affinity Capture-MS Homo sapiens
127 SLX4  
Affinity Capture-MS Homo sapiens
128 MIP  
Affinity Capture-MS Homo sapiens
129 APTX  
Affinity Capture-MS Homo sapiens
130 SCGB1D1  
Affinity Capture-MS Homo sapiens
131 RBM24 221662
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 WWOX 51741
Affinity Capture-MS Homo sapiens
133 SH2D3A  
Affinity Capture-MS Homo sapiens
134 NMB  
Affinity Capture-MS Homo sapiens
135 EMC4 51234
Affinity Capture-MS Homo sapiens
136 ZNF154  
Affinity Capture-MS Homo sapiens
137 CDK15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 C1orf35  
Affinity Capture-MS Homo sapiens
139 SSBP2  
Affinity Capture-MS Homo sapiens
140 TREX2  
Affinity Capture-MS Homo sapiens
141 PTDSS1 9791
Affinity Capture-MS Homo sapiens
142 FBXO44  
Affinity Capture-MS Homo sapiens
143 S100A9 6280
Affinity Capture-MS Homo sapiens
144 PKP1 5317
Affinity Capture-MS Homo sapiens
145 FAM227B  
Affinity Capture-MS Homo sapiens
146 ERCC3  
Affinity Capture-MS Homo sapiens
147 MBNL1 4154
Affinity Capture-MS Homo sapiens
148 KIR3DS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 CALML5 51806
Affinity Capture-MS Homo sapiens
150 TEFM  
Affinity Capture-MS Homo sapiens
151 SH3GLB1 51100
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 AIRE  
Affinity Capture-MS Homo sapiens
153 TSPAN6 7105
Affinity Capture-MS Homo sapiens
154 PINK1  
Affinity Capture-MS Homo sapiens
155 GPR18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 GOT1 2805
Affinity Capture-MS Homo sapiens
157 STK11 6794
Affinity Capture-MS Homo sapiens
158 ITGA9 3680
Affinity Capture-MS Homo sapiens
159 OR2A4 79541
Affinity Capture-MS Homo sapiens
160 ANXA2 302
Affinity Capture-MS Homo sapiens
161 GABPA 2551
Affinity Capture-MS Homo sapiens
162 CCR1  
Affinity Capture-MS Homo sapiens
163 GUCY1A3  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SERPINB3 is involved
PathwayEvidenceSource
Immune System TAS Reactome
Innate Immune System TAS Reactome
Neutrophil degranulation TAS Reactome





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