Gene description for MTA1
Gene name metastasis associated 1
Gene symbol MTA1
Other names/aliases -
Species Homo sapiens
 Database cross references - MTA1
ExoCarta ExoCarta_9112
Vesiclepedia VP_9112
Entrez Gene 9112
HGNC 7410
MIM 603526
UniProt Q13330  
 MTA1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 34887515    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for MTA1
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 ISS
    chromatin binding GO:0003682 IEA
    transcription coactivator activity GO:0003713 IBA
    transcription coactivator activity GO:0003713 IMP
    transcription corepressor activity GO:0003714 IBA
    transcription corepressor activity GO:0003714 IMP
    protein binding GO:0005515 IPI
    histone deacetylase binding GO:0042826 IBA
    metal ion binding GO:0046872 IEA
    RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IBA
    double-strand break repair GO:0006302 IBA
    double-strand break repair GO:0006302 IMP
    chromatin remodeling GO:0006338 IDA
    signal transduction GO:0007165 TAS
    response to ionizing radiation GO:0010212 IBA
    response to ionizing radiation GO:0010212 IDA
    circadian regulation of gene expression GO:0032922 ISS
    regulation of cell fate specification GO:0042659 NAS
    entrainment of circadian clock by photoperiod GO:0043153 ISS
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IMP
    locomotor rhythm GO:0045475 ISS
    negative regulation of gene expression, epigenetic GO:0045814 IMP
    negative regulation of DNA-templated transcription GO:0045892 NAS
    positive regulation of DNA-templated transcription GO:0045893 NAS
    positive regulation of protein autoubiquitination GO:1902499 IDA
    regulation of stem cell differentiation GO:2000736 NAS
Subcellular Localization
    nucleus GO:0005634 IDA
    nuclear envelope GO:0005635 IDA
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    microtubule GO:0005874 IDA
    NuRD complex GO:0016581 IBA
    NuRD complex GO:0016581 IDA
    NuRD complex GO:0016581 NAS
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified MTA1 in sEVs
1
Experiment ID 489
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 1203
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
6
Experiment ID 488
MISEV standards
✔ Biophysical techniques
✔ Enriched markers
✔ Negative markers
✔ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MTA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 ATR  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
3 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
4 GATAD2B 57459
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
5 KPNA3 3839
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
6 HDAC2 3066
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
7 CCNH  
Affinity Capture-Western Homo sapiens
8 KPNA1 3836
Affinity Capture-MS Homo sapiens
9 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
10 CTBP2 1488
Affinity Capture-MS Homo sapiens
11 SH3GL1 6455
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
12 TSHZ3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 CSNK1G2 1455
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
14 FHL3 2275
Two-hybrid Homo sapiens
15 ACTC1 70
Proximity Label-MS Homo sapiens
16 TOP1 7150
Affinity Capture-MS Homo sapiens
17 TIGD6  
Affinity Capture-MS Homo sapiens
18 BRD2  
Affinity Capture-MS Homo sapiens
19 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
20 SAP30 8819
Affinity Capture-MS Homo sapiens
21 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
22 PARK7 11315
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
23 SOX2  
Affinity Capture-MS Homo sapiens
24 CENPA  
Proximity Label-MS Homo sapiens
25 C9orf78 51759
Affinity Capture-MS Homo sapiens
26 BLOC1S1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
27 TCF19  
Affinity Capture-MS Homo sapiens
28 PLEKHG4  
Two-hybrid Homo sapiens
29 WDR76  
Affinity Capture-MS Homo sapiens
30 ZNF423  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 Cdk2ap1  
Affinity Capture-MS Mus musculus
32 SSRP1 6749
Affinity Capture-MS Homo sapiens
33 SMARCA1 6594
Affinity Capture-MS Homo sapiens
34 CDK2AP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 NR2C2  
Affinity Capture-Western Homo sapiens
36 KRT40  
Two-hybrid Homo sapiens
37 ARID4B  
Affinity Capture-MS Homo sapiens
38 ZNF512B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 SIN3B  
Affinity Capture-MS Homo sapiens
40 MBD3L2  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
41 THRSP  
Affinity Capture-MS Homo sapiens
42 Kctd5  
Affinity Capture-MS Mus musculus
43 EED  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 ZNF219  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 NR2C1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
46 TRIM25 7706
Biochemical Activity Homo sapiens
47 PHF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
48 CHD3 1107
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
49 SALL4  
Affinity Capture-MS Homo sapiens
50 CPNE5 57699
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 LMO4  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
52 BCL11B  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
53 KIF14 9928
Affinity Capture-MS Homo sapiens
54 ESR1  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
55 FOXP1 27086
Affinity Capture-Western Homo sapiens
56 SOX6  
Proximity Label-MS Homo sapiens
57 HMGA1 3159
Affinity Capture-MS Homo sapiens
58 PHF20L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 RBBP7 5931
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 SHPRH  
Affinity Capture-MS Homo sapiens
61 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
62 KPNA4 3840
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
63 RBX1 9978
Affinity Capture-Western Homo sapiens
64 CUL4B 8450
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
65 PITX3  
Co-localization Homo sapiens
66 HIST1H3C 8352
Affinity Capture-MS Homo sapiens
67 HIC1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
68 C17orf49 124944
Affinity Capture-MS Homo sapiens
69 LYN 4067
Proximity Label-MS Homo sapiens
70 UBE2I 7329
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
71 BAG6 7917
Affinity Capture-MS Homo sapiens
72 ITGB3BP  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
73 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
74 GPR183  
Two-hybrid Homo sapiens
75 HIST1H3J 8356
Affinity Capture-MS Homo sapiens
76 ZEB2  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
77 MNAT1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
78 TSHZ2  
Affinity Capture-MS Homo sapiens
79 CYSRT1 375791
Two-hybrid Homo sapiens
80 NTRK1 4914
Affinity Capture-MS Homo sapiens
81 AIM2  
Affinity Capture-MS Homo sapiens
82 KRTAP10-8  
Two-hybrid Homo sapiens
83 ZBTB46  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 BPTF 2186
Affinity Capture-MS Homo sapiens
85 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
86 SUMO2 6613
Reconstituted Complex Homo sapiens
87 BRMS1L  
Affinity Capture-MS Homo sapiens
88 MYBL2 4605
Affinity Capture-MS Homo sapiens
89 MBD2 8932
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
90 CHD5 26038
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
91 SUDS3  
Affinity Capture-MS Homo sapiens
92 L3MBTL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 TEX11  
Two-hybrid Homo sapiens
94 SAT1  
Two-hybrid Homo sapiens
95 VPS18 57617
Affinity Capture-MS Homo sapiens
96 CEBPA  
Proximity Label-MS Homo sapiens
97 GATAD1  
Affinity Capture-MS Homo sapiens
98 RAD21 5885
Co-fractionation Homo sapiens
99 NOTCH2NL 388677
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
100 BCL11A 53335
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
101 NUMA1 4926
Affinity Capture-MS Homo sapiens
102 ZBTB2 57621
Affinity Capture-MS Homo sapiens
103 HIST1H3F 8968
Affinity Capture-MS Homo sapiens
104 HIST1H3A 8350
Proximity Label-MS Homo sapiens
105 CDK7 1022
Affinity Capture-Western Homo sapiens
106 STMN2  
Affinity Capture-MS Homo sapiens
107 HIST2H3C 126961
Affinity Capture-Western Homo sapiens
108 MAGEA11  
Two-hybrid Homo sapiens
109 SMARCA5 8467
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
110 IKZF3  
Affinity Capture-MS Homo sapiens
111 NELFCD 51497
Two-hybrid Homo sapiens
112 POLD3  
Affinity Capture-Western Homo sapiens
113 BTF3 689
Affinity Capture-MS Homo sapiens
114 AKAP13 11214
Affinity Capture-MS Homo sapiens
115 H1F0 3005
Affinity Capture-MS Homo sapiens
116 IKZF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
117 RBBP4 5928
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 HIST3H3 8290
Protein-peptide Homo sapiens
119 BUD13  
Affinity Capture-MS Homo sapiens
120 JUN 3725
Reconstituted Complex Homo sapiens
121 SGTB  
Affinity Capture-MS Homo sapiens
122 SIX3  
Affinity Capture-Western Homo sapiens
123 DNMT3B  
Affinity Capture-Western Homo sapiens
124 LIN9  
Affinity Capture-MS Homo sapiens
125 ZNF521  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 Mta2 23942
Affinity Capture-MS Mus musculus
127 FAM64A 54478
Affinity Capture-MS Homo sapiens
128 ZMYND8 23613
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 DLST 1743
Affinity Capture-MS Homo sapiens
130 ASF1A 25842
Proximity Label-MS Homo sapiens
131 CLASRP  
Affinity Capture-MS Homo sapiens
132 TRIM33 51592
Co-fractionation Homo sapiens
133 HJURP  
Affinity Capture-MS Homo sapiens
134 CSNK2B 1460
Affinity Capture-MS Homo sapiens
135 DDB1 1642
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
136 HIST1H3H 8357
Affinity Capture-MS Homo sapiens
137 RNF2  
Affinity Capture-MS Homo sapiens
138 Bsdc1  
Affinity Capture-MS Mus musculus
139 MECOM 2122
Affinity Capture-MS Homo sapiens
140 HAT1 8520
Affinity Capture-MS Homo sapiens
141 NANOG  
Affinity Capture-MS Homo sapiens
142 MYH10 4628
Co-fractionation Homo sapiens
143 KHDRBS2  
Two-hybrid Homo sapiens
144 NFATC2  
Affinity Capture-MS Homo sapiens
145 BRD3 8019
Affinity Capture-MS Homo sapiens
146 LIN52  
Affinity Capture-MS Homo sapiens
147 MDM2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
148 SNAI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
149 NAA10 8260
Affinity Capture-Western Homo sapiens
150 SUZ12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
151 EIF3D 8664
Affinity Capture-MS Homo sapiens
152 CHD7  
Affinity Capture-MS Homo sapiens
153 HIF1A 3091
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
154 GATAD2A 54815
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 DZIP3  
Affinity Capture-MS Homo sapiens
156 Cbx1  
Affinity Capture-MS Mus musculus
157 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
158 PARP1 142
Affinity Capture-MS Homo sapiens
159 TRPS1  
Affinity Capture-MS Homo sapiens
160 SAP130  
Affinity Capture-MS Homo sapiens
161 TP53 7157
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
162 SIN3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 MBD3 53615
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
164 XRCC6 2547
Proximity Label-MS Homo sapiens
165 NUCKS1 64710
Affinity Capture-MS Homo sapiens
166 DPY30 84661
Affinity Capture-MS Homo sapiens
167 NBPF19  
Two-hybrid Homo sapiens
168 HMGN5 79366
Affinity Capture-MS Homo sapiens
169 LZTS2 84445
Two-hybrid Homo sapiens
170 Tnks1bp1  
Affinity Capture-MS Mus musculus
171 HDAC1 3065
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
172 CHD4 1108
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
173 SALL1 6299
Affinity Capture-MS Homo sapiens
174 SIRT1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 MTA2 9219
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
176 ZFPM1 161882
Co-crystal Structure Homo sapiens
177 TOP2A 7153
Affinity Capture-MS Homo sapiens
178 ZFPM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
179 HMGXB4 10042
Affinity Capture-MS Homo sapiens
180 DNAJA2 10294
Co-fractionation Homo sapiens
181 FAM219A 203259
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 KDM1A 23028
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
183 Actr1b 226977
Affinity Capture-MS Mus musculus
184 Mbd2  
Affinity Capture-MS Mus musculus
185 EZH2  
Affinity Capture-MS Homo sapiens
186 H2AFZ 3015
Affinity Capture-MS Homo sapiens
187 LRRK2 120892
Reconstituted Complex Homo sapiens
188 HSF1  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
189 NACC2  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
190 MTA3 57504
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
191 TXNIP 10628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 MBD3L1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
193 SERBP1 26135
Affinity Capture-MS Homo sapiens
194 MTF2  
Affinity Capture-MS Homo sapiens
195 PWWP2A  
Affinity Capture-MS Homo sapiens
196 VIM 7431
Affinity Capture-MS Homo sapiens
197 DNMT1 1786
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
198 RPA3 6119
Proximity Label-MS Homo sapiens
199 LIN37  
Affinity Capture-MS Homo sapiens
200 EP300 2033
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which MTA1 is involved
PathwayEvidenceSource
Adipogenesis IEA Reactome
Chromatin modifying enzymes TAS Reactome
Chromatin organization TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression IEA Reactome
Gene expression (Transcription) IEA Reactome
Gene expression (Transcription) TAS Reactome
HDACs deacetylate histones TAS Reactome
Infectious disease TAS Reactome
Intracellular signaling by second messengers IEA Reactome
Intracellular signaling by second messengers TAS Reactome
Metabolism of proteins TAS Reactome
PIP3 activates AKT signaling IEA Reactome
PIP3 activates AKT signaling TAS Reactome
Positive epigenetic regulation of rRNA expression IEA Reactome
Post-translational protein modification TAS Reactome
Potential therapeutics for SARS TAS Reactome
PTEN Regulation IEA Reactome
PTEN Regulation TAS Reactome
Regulation of endogenous retroelements IEA Reactome
Regulation of endogenous retroelements by KRAB-ZFP proteins IEA Reactome
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) IEA Reactome
Regulation of PTEN gene transcription IEA Reactome
Regulation of PTEN gene transcription TAS Reactome
RNA Polymerase I Promoter Clearance TAS Reactome
RNA Polymerase I Transcription TAS Reactome
RNA Polymerase I Transcription Initiation TAS Reactome
SARS-CoV Infections TAS Reactome
Signal Transduction IEA Reactome
Signal Transduction TAS Reactome
SUMO E3 ligases SUMOylate target proteins TAS Reactome
SUMOylation TAS Reactome
SUMOylation of transcription factors TAS Reactome
Transcriptional regulation of brown and beige adipocyte differentiation IEA Reactome
Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 IEA Reactome
Viral Infection Pathways TAS Reactome





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