Gene description for CDH9
Gene name cadherin 9, type 2 (T1-cadherin)
Gene symbol CDH9
Other names/aliases -
Species Homo sapiens
 Database cross references - CDH9
ExoCarta ExoCarta_1007
Vesiclepedia VP_1007
Entrez Gene 1007
HGNC 1768
MIM 609974
UniProt Q9ULB4  
 CDH9 identified in sEVs derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for CDH9
Molecular Function
    calcium ion binding GO:0005509 IEA
    beta-catenin binding GO:0008013 IBA
    cadherin binding GO:0045296 IBA
Biological Process
    cell morphogenesis GO:0000902 IBA
    cell-cell junction assembly GO:0007043 IBA
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IEA
    synapse assembly GO:0007416 IEA
    calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339 IBA
    cell migration GO:0016477 IBA
    adherens junction organization GO:0034332 IBA
    cell-cell adhesion mediated by cadherin GO:0044331 IBA
    cell-cell adhesion GO:0098609 NAS
    synaptic membrane adhesion GO:0099560 IBA
Subcellular Localization
    plasma membrane GO:0005886 TAS
    adherens junction GO:0005912 IBA
    catenin complex GO:0016342 IBA
    presynaptic membrane GO:0042734 IEA
    postsynaptic membrane GO:0045211 IEA
 Experiment description of studies that identified CDH9 in sEVs
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for CDH9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KIF14 9928
Affinity Capture-MS Homo sapiens
2 MEOX2  
Two-hybrid Homo sapiens
3 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
4 CTNNB1 1499
Affinity Capture-Western Homo sapiens
5 KIF20A 10112
Affinity Capture-MS Homo sapiens
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