Gene description for CORO2B
Gene name coronin, actin binding protein, 2B
Gene symbol CORO2B
Other names/aliases CLIPINC
Species Homo sapiens
 Database cross references - CORO2B
ExoCarta ExoCarta_10391
Vesiclepedia VP_10391
Entrez Gene 10391
HGNC 2256
MIM 605002
UniProt Q9UQ03  
 CORO2B identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for CORO2B
Molecular Function
    actin filament binding GO:0051015 IBA
    actin binding GO:0003779 NAS
    protein binding GO:0005515 IPI
Biological Process
    actin cytoskeleton organization GO:0030036 NAS
Subcellular Localization
    membrane GO:0016020 NAS
    cytoplasm GO:0005737 IEA
    actin cytoskeleton GO:0015629 NAS
 Experiment description of studies that identified CORO2B in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CORO2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TSC22D1 8848
Two-hybrid Homo sapiens
2 VCL 7414
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which CORO2B is involved
No pathways found





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