Gene description for SPINK5
Gene name	serine peptidase inhibitor, Kazal type 5
Gene symbol	SPINK5
Other names/aliases	LEKTI LETKI NETS NS VAKTI
Species	Homo sapiens
Database cross references - SPINK5
ExoCarta	ExoCarta_11005
Vesiclepedia	VP_11005
Entrez Gene	11005
HGNC	15464
MIM	605010
UniProt	Q9NQ38
SPINK5 identified in sEVs derived from the following tissue/cell type
Keratinocytes	19530224
Keratinocytes	19530224

Gene ontology annotations for SPINK5

Molecular Function     serine-type endopeptidase inhibitor activity GO:0004867 IBA     serine-type endopeptidase inhibitor activity GO:0004867 IDA Biological Process     negative regulation of antibacterial peptide production GO:0002787 IEA     epidermal cell differentiation GO:0009913 IDA     negative regulation of angiogenesis GO:0016525 TAS     cell differentiation GO:0030154 IBA     regulation of cell adhesion GO:0030155 IEA     extracellular matrix organization GO:0030198 TAS     epithelial cell differentiation GO:0030855 TAS     hair cell differentiation GO:0035315 TAS     regulation of T cell differentiation GO:0045580 TAS     negative regulation of proteolysis GO:0045861 IEA     negative regulation of immune response GO:0050777 TAS     regulation of timing of anagen GO:0051884 TAS Subcellular Localization     extracellular region GO:0005576 IBA     extracellular region GO:0005576 IDA     extracellular region GO:0005576 NAS     extracellular region GO:0005576 TAS     cytoplasm GO:0005737 IDA     endoplasmic reticulum GO:0005783 IDA     endoplasmic reticulum membrane GO:0005789 IDA     cytosol GO:0005829 IDA     cell cortex GO:0005938 IDA     intracellular membrane-bounded organelle GO:0043231 IDA     perinuclear region of cytoplasm GO:0048471 IDA     epidermal lamellar body GO:0097209 IDA