|
 Gene description for ARHGAP33 |
| Gene name |
Rho GTPase activating protein 33 |
| Gene symbol |
ARHGAP33 |
| Other names/aliases |
NOMA-GAP
SNX26
TCGAP |
| Species |
Homo sapiens |
| Database cross references - ARHGAP33 |
| ExoCarta |
ExoCarta_115703 |
| Vesiclepedia |
VP_115703 |
| Entrez Gene |
115703 |
| HGNC |
23085 |
| MIM |
614902 |
| UniProt |
O14559
|
| ARHGAP33 identified in exosomes derived from the following tissue/cell type |
|
Hepatocytes
|
26054723
|
|
Squamous carcinoma cells
|
20124223
|
| Gene ontology annotations for ARHGAP33 |
|
|
| Experiment description of studies that identified ARHGAP33 in exosomes |
| 1 |
| Experiment ID |
237 |
| MISEV standards |
|
✔
EM
|
EV Biophysical techniques |
|
✔
TSG101|Alix|HSC70|GAPDH
|
EV Enriched markers |
|
✔
HSP90B1
|
EV Negative markers |
|
✔
qNano
|
EV Particle analysis
|
|
| Identified molecule |
mRNA
|
| Identification method |
RNA Sequencing
|
| PubMed ID |
26054723
|
| Organism |
Homo sapiens |
| Experiment description |
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs |
| Authors |
He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N |
| Journal name |
Carcinogenesis
|
| Publication year |
2015 |
| Sample |
Hepatocytes |
| Sample name |
MIHA |
| Isolation/purification methods |
Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient |
| Flotation density |
1.13-1.19 g/mL
|
| Molecules identified in the study |
Protein
RNA |
| Methods used in the study |
Western blotting
Mass spectrometry
RNA Sequencing |
|
|
| 2 |
| Experiment ID |
191 |
| MISEV standards |
|
✘
|
EV Biophysical techniques |
|
✔
Alix|CD81|CD9
|
EV Enriched markers |
|
✘
|
EV Negative markers |
|
✘
|
EV Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
20124223
|
| Organism |
Homo sapiens |
| Experiment description |
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. |
| Authors |
Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK. |
| Journal name |
Mol Cell Proteomics
|
| Publication year |
2010 |
| Sample |
Squamous carcinoma cells |
| Sample name |
Squamous carcinoma cell (A431) |
| Isolation/purification methods |
Differential centrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry |
|
|
| Protein-protein interactions for ARHGAP33 |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
| Pathways in which ARHGAP33 is involved |
|
|
|
