Gene description for Eif2s1
Gene name	eukaryotic translation initiation factor 2, subunit 1 alpha
Gene symbol	Eif2s1
Other names/aliases	0910001O23Rik 2410026C18Rik 35kDa Eif2a eIF2alpha
Species	Mus musculus
Database cross references - Eif2s1
ExoCarta	ExoCarta_13665
Entrez Gene	13665
UniProt	Q6ZWX6
Eif2s1 identified in exosomes derived from the following tissue/cell type
Neural stem cells	25242146

Gene ontology annotations for Eif2s1

Molecular Function     ribosome binding GO:0043022 ISO     RNA binding GO:0003723 IEA     translation initiation factor activity GO:0003743 ISO     protein binding GO:0005515 IPI     poly(A) RNA binding GO:0044822 ISO     nucleic acid binding GO:0003676 IEA Biological Process     activation of mitophagy in response to mitochondrial depolarization GO:0098779 ISO     translation GO:0006412 ISO     protein autophosphorylation GO:0046777 IDA     translational initiation GO:0006413 ISO     positive regulation of defense response to virus by host GO:0002230 ISO     regulation of translation GO:0006417 IEA     regulation of translational initiation in response to stress GO:0043558 IDA Subcellular Localization     extracellular exosome GO:0070062 ISO     eukaryotic translation initiation factor 2 complex GO:0005850 IBA     cytoplasmic stress granule GO:0010494 IDA     cytoplasm GO:0005737 IDA     multi-eIF complex GO:0043614 IBA     nucleus GO:0005634 IDA     ribosome GO:0005840 IBA     membrane GO:0016020 ISO     eukaryotic translation initiation factor 2B complex GO:0005851 ISO     eukaryotic 48S preinitiation complex GO:0033290 IBA