Gene description for Srsf6
Gene name
serine/arginine-rich splicing factor 6
Gene symbol
Srsf6
Other names/aliases
1210001E11Rik AI314910 AW146126 Sfrs6
Species
Mus musculus
Database cross references - Srsf6
ExoCarta
ExoCarta_67996
Vesiclepedia
VP_67996
Entrez Gene
67996
UniProt
Q3TWW8
Srsf6 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Srsf6
Experiment description of studies that identified Srsf6 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Srsf6
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SRSF4
6429
Two-hybrid
Homo sapiens
2
NXF1
10482
Two-hybrid
Homo sapiens
3
PNO1
56902
Two-hybrid
Homo sapiens
4
Eif2s1
13665
Two-hybrid
Mus musculus
5
Mapt
Affinity Capture-MS
Mus musculus
6
SF3B4
10262
Two-hybrid
Homo sapiens
7
LUC7L
55692
Two-hybrid
Homo sapiens
8
Cpsf6
Two-hybrid
Mus musculus
9
Fancd2
Affinity Capture-MS
Mus musculus
10
LPAR1
1902
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which Srsf6 is involved
No pathways found