Gene description for KCTD11
Gene name potassium channel tetramerization domain containing 11
Gene symbol KCTD11
Other names/aliases C17orf36
KCASH1
REN
REN/KCTD11
Species Homo sapiens
 Database cross references - KCTD11
ExoCarta ExoCarta_147040
Vesiclepedia VP_147040
Entrez Gene 147040
HGNC 21302
MIM 609848
UniProt Q693B1  
 KCTD11 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for KCTD11
Molecular Function
    transferase activity GO:0016740 IEA
    identical protein binding GO:0042802 IPI
Biological Process
    protein ubiquitination GO:0016567 IEA
    positive regulation of neuron differentiation GO:0045666 IBA
    protein homooligomerization GO:0051260 IEA
 Experiment description of studies that identified KCTD11 in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for KCTD11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CTNNB1 1499
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
2 CUL3 8452
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
3 USP21  
Affinity Capture-Western Homo sapiens
4 HDAC1 3065
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
5 KCTD6  
Affinity Capture-MS Homo sapiens
6 KCTD11 147040
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which KCTD11 is involved
No pathways found





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