Gene description for Phb |
Gene name |
prohibitin |
Gene symbol |
Phb |
Other names/aliases |
Bap32 |
Species |
Mus musculus |
Database cross references - Phb |
ExoCarta |
ExoCarta_18673 |
Vesiclepedia |
VP_18673 |
Entrez Gene |
18673 |
UniProt |
P67778
|
Phb identified in exosomes derived from the following tissue/cell type |
Melanoma cells
|
34957415
|
Melanoma cells
|
34957415
|
Pancreatic cells
|
19351151
|
Gene ontology annotations for Phb |
|
Experiment description of studies that identified Phb in exosomes |
1 |
Experiment ID |
1117 |
MISEV standards |
✘
|
EV Biophysical techniques |
✔
Cd81|Icam1
|
EV Enriched markers |
✘
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
34957415
|
Organism |
Mus musculus |
Experiment description |
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors |
GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year |
2021 |
Sample |
Melanoma cells |
Sample name |
B16-F1R2 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
2 |
Experiment ID |
1118 |
MISEV standards |
✘
|
EV Biophysical techniques |
✔
Cd81|Icam1
|
EV Enriched markers |
✘
|
EV Negative markers |
✔
NTA
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
34957415
|
Organism |
Mus musculus |
Experiment description |
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors |
GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year |
2021 |
Sample |
Melanoma cells |
Sample name |
B16-F1R2 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Western blotting Mass spectrometry |
|
|
3 |
Experiment ID |
188 |
MISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
GAPDH|UCHL1|HSP90
|
EV Enriched markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
19351151
|
Organism |
Mus musculus |
Experiment description |
Characterization of vesicles secreted from insulinoma NIT-1 cells. |
Authors |
Lee HS, Jeong J, Lee KJ. |
Journal name |
J Proteome Res
|
Publication year |
2009 |
Sample |
Pancreatic cells |
Sample name |
Pancreatic beta cell (NIT-1) |
Isolation/purification methods |
Differential centrifugation Sucrose density gradient |
Flotation density |
-
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
Protein-protein interactions for Phb |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which Phb is involved |
No pathways found
|
|
|