Experiment description of studies that identified Sars in sEVs

1 Experiment ID 907 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 210 MISEV standards ✔ EM Biophysical techniques ✔ CD81|FLOT1 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23260141     Organism Mus musculus Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration. Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL." Journal name Cell Publication year 2012 Sample Fibroblasts Sample name Normal-Fibroblasts (L cells) Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 908 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Sars

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Snx5 69178 Co-fractionation Mus musculus 2 RNF40 9810 Affinity Capture-MS Homo sapiens 3 Uba5   Co-fractionation Mus musculus 4 STRAP 11171 Affinity Capture-MS Homo sapiens 5 Tmem173   Proximity Label-MS Mus musculus 6 MRPL57   Affinity Capture-MS Homo sapiens 7 Atxn1   Affinity Capture-MS Mus musculus 8 Rpl19 19921 Co-fractionation Mus musculus 9 Kctd13   Affinity Capture-MS Mus musculus 10 GPBP1   Affinity Capture-MS Homo sapiens 11 Tia1   Affinity Capture-MS Mus musculus 12 SETDB1   Affinity Capture-MS Homo sapiens 13 Rpl18a 76808 Co-fractionation Mus musculus 14 IBTK 25998 Affinity Capture-MS Homo sapiens 15 Ttc1   Co-fractionation Mus musculus 16 Eftud2 20624 Co-fractionation Mus musculus 17 PTPRS 5802 Affinity Capture-MS Homo sapiens 18 PARP10 84875 Affinity Capture-MS Homo sapiens View the network

Pathways in which Sars is involved

No pathways found