Gene description for Sars
Gene name seryl-aminoacyl-tRNA synthetase
Gene symbol Sars
Other names/aliases Sars1
Species Mus musculus
 Database cross references - Sars
ExoCarta ExoCarta_20226
Entrez Gene 20226
UniProt P26638  
 Sars identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Sars
Molecular Function
    serine-tRNA ligase activity GO:0004828 IBA
    ligase activity GO:0016874 IEA
    nucleotide binding GO:0000166 IEA
    ATP binding GO:0005524 IEA
    aminoacyl-tRNA ligase activity GO:0004812 IEA
Biological Process
    tRNA aminoacylation for protein translation GO:0006418 IEA
    translation GO:0006412 IEA
    seryl-tRNA aminoacylation GO:0006434 IBA
Subcellular Localization
    mitochondrion GO:0005739 IDA
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 ISO
 Experiment description of studies that identified Sars in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Sars
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Sars is involved
No pathways found

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