Gene description for Cblb
Gene name	Casitas B-lineage lymphoma b
Gene symbol	Cblb
Other names/aliases	AI429560 AI851073 Cbl-b
Species	Mus musculus
Database cross references - Cblb
ExoCarta	ExoCarta_208650
Vesiclepedia	VP_208650
Entrez Gene	208650
UniProt	Q3TTA7
Cblb identified in sEVs derived from the following tissue/cell type
Mast cells	17486113

Gene ontology annotations for Cblb

Molecular Function     phosphotyrosine residue binding GO:0001784 IEA     ubiquitin-protein transferase activity GO:0004842 IEA     calcium ion binding GO:0005509 IEA     protein binding GO:0005515 IPI     protein kinase binding GO:0019901 ISO     receptor tyrosine kinase binding GO:0030971 IBA     ubiquitin protein ligase activity GO:0061630 IBA Biological Process     positive regulation of T cell anergy GO:0002669 IMP     T cell anergy GO:0002870 IMP     immune response GO:0006955 IMP     signal transduction GO:0007165 IBA     protein ubiquitination GO:0016567 IEA     peptidyl-amino acid modification GO:0018193 IDA     regulation of cell adhesion GO:0030155 IMP     protein catabolic process GO:0030163 IMP     positive regulation of protein ubiquitination GO:0031398 IDA     intracellular signal transduction GO:0035556 IMP     CD4-positive, alpha-beta T cell proliferation GO:0035739 IMP     negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 IBA     T cell activation GO:0042110 IMP     negative regulation of apoptotic process GO:0043066 ISO     regulation of GTPase activity GO:0043087 IMP     regulation of protein binding GO:0043393 IMP     positive regulation of protein catabolic process GO:0045732 IMP     T cell receptor signaling pathway GO:0050852 IMP     regulation of T cell receptor signaling pathway GO:0050856 ISO     negative regulation of T cell receptor signaling pathway GO:0050860 IMP     regulation of postsynaptic neurotransmitter receptor internalization GO:0099149 IDA     regulation protein catabolic process at postsynapse GO:0140252 IDA     negative regulation of CD4-positive, alpha-beta T cell proliferation GO:2000562 IMP     regulation of platelet-derived growth factor receptor-alpha signaling pathway GO:2000583 IMP Subcellular Localization     nucleoplasm GO:0005654 IEA     nucleoplasm GO:0005654 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IBA     membrane raft GO:0045121 IBA     postsynapse GO:0098794 IDA     glutamatergic synapse GO:0098978 IDA