Gene description for AMY1A
Gene name amylase, alpha 1A (salivary)
Gene symbol AMY1A
Other names/aliases AMY1
Species Homo sapiens
 Database cross references - AMY1A
ExoCarta ExoCarta_276
Entrez Gene 276
HGNC 474
MIM 104700
UniProt P04745  
 AMY1A identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for AMY1A
Molecular Function
    metal ion binding GO:0046872 IEA
    protein binding GO:0005515 IPI
    alpha-amylase activity GO:0004556 IEA
Biological Process
    carbohydrate metabolic process GO:0005975 IEA
    digestion GO:0007586 TAS
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    extracellular space GO:0005615 IDA
 Experiment description of studies that identified AMY1A in exosomes
1
Experiment ID 66
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for AMY1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 AKAP1  
Affinity Capture-Western Homo sapiens
2 AKAP8  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
3 CDK2AP1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which AMY1A is involved
PathwayEvidenceSource
Digestion of dietary carbohydrate TAS Reactome





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