Gene description for SEC14L4
Gene name SEC14-like 4 (S. cerevisiae)
Gene symbol SEC14L4
Other names/aliases TAP3
Species Homo sapiens
 Database cross references - SEC14L4
ExoCarta ExoCarta_284904
Vesiclepedia VP_284904
Entrez Gene 284904
HGNC 20627
MIM 612825
UniProt Q9UDX3  
 SEC14L4 identified in exosomes derived from the following tissue/cell type
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for SEC14L4
Molecular Function
    protein binding GO:0005515 IPI
    lipid binding GO:0008289 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
 Experiment description of studies that identified SEC14L4 in exosomes
1
Experiment ID 254
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 257
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
3
Experiment ID 260
MISEV standards
EM
Biophysical techniques
TSG101|FLOT1|CD81
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for SEC14L4
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SERTAD1  
Two-hybrid Homo sapiens
2 SEC14L3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 CTAG1B  
Two-hybrid Homo sapiens
4 REL 5966
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
5 CTAG1A  
Two-hybrid Homo sapiens
6 KRT34  
Two-hybrid Homo sapiens
7 USHBP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
8 PLEKHF2 79666
Two-hybrid Homo sapiens
9 BMF  
Two-hybrid Homo sapiens
10 MEOX2  
Two-hybrid Homo sapiens
11 RHOU 58480
Reconstituted Complex Homo sapiens
12 PAX5  
Two-hybrid Homo sapiens
13 INCA1  
Two-hybrid Homo sapiens
14 ENTHD2  
Two-hybrid Homo sapiens
15 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
16 TCF4  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
17 CRX  
Two-hybrid Homo sapiens
18 TRIM54  
Two-hybrid Homo sapiens
19 HAO2  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which SEC14L4 is involved
No pathways found





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