Gene description for ANGPT2
Gene name
angiopoietin 2
Gene symbol
ANGPT2
Other names/aliases
AGPT2 ANG2
Species
Homo sapiens
Database cross references - ANGPT2
ExoCarta
ExoCarta_285
Vesiclepedia
VP_285
Entrez Gene
285
HGNC
485
MIM
601922
UniProt
O15123
ANGPT2 identified in exosomes derived from the following tissue/cell type
Plasma
34112803
Plasma
34112803
Gene ontology annotations for ANGPT2
Experiment description of studies that identified ANGPT2 in exosomes
1
Experiment ID
525
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
ELISA
PubMed ID
34112803
Organism
Homo sapiens
Experiment description
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Authors
"Lima LG, Ham S, Shin H, Chai EPZ, Lek ESH, Lobb RJ, Müller AF, Mathivanan S, Yeo B, Choi Y, Parker BS, Möller A. "
Journal name
Nat Commun
Publication year
2021
Sample
Plasma
Sample name
Pooled plasma from healthy subjects
Isolation/purification methods
Size exclusion chromatography Centrifugal ultrafiltration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
ELISA
2
Experiment ID
526
MISEV standards
✔
EM
Biophysical techniques
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
ELISA
PubMed ID
34112803
Organism
Homo sapiens
Experiment description
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Authors
"Lima LG, Ham S, Shin H, Chai EPZ, Lek ESH, Lobb RJ, Müller AF, Mathivanan S, Yeo B, Choi Y, Parker BS, Möller A. "
Journal name
Nat Commun
Publication year
2021
Sample
Plasma
Sample name
Pooled plasma from breast cancer patients
Isolation/purification methods
Size exclusion chromatography Centrifugal ultrafiltration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
ELISA
Protein-protein interactions for ANGPT2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
ITGB1
3688
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
2
TEK
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
3
IQCB1
Affinity Capture-MS
Homo sapiens
4
ANXA7
310
Two-hybrid
Homo sapiens
5
ITGAV
3685
Affinity Capture-Western
Homo sapiens
6
HECTD3
79654
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
ZZEF1
23140
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
8
ITGA5
3678
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
9
CSNK2B
1460
Two-hybrid
Homo sapiens
10
FBXO28
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
11
CDKN1A
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which ANGPT2 is involved