Experiment description of studies that identified TMEM230 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for TMEM230

Protein Interactor ExoCarta ID Identification method PubMed Species 1 GJD3   Proximity Label-MS Homo sapiens 2 AQP2 359 Two-hybrid Homo sapiens 3 ATP11C 286410 Affinity Capture-MS Homo sapiens 4 RPN2 6185 Proximity Label-MS Homo sapiens 5 MBLAC2 153364 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 CANX 821 Affinity Capture-MS Homo sapiens 7 ATP11A 23250 Affinity Capture-MS Homo sapiens 8 LAMTOR1 55004 Proximity Label-MS Homo sapiens 9 METTL7A 25840 Proximity Label-MS Homo sapiens 10 LAMP3   Proximity Label-MS Homo sapiens 11 MTNR1B   Two-hybrid Homo sapiens 12 TMEM30B 161291 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 BCAP31 10134 Proximity Label-MS Homo sapiens 14 HSD3B7 80270 Proximity Label-MS Homo sapiens 15 MTNR1A   Two-hybrid Homo sapiens 16 LAMP2 3920 Proximity Label-MS Homo sapiens 17 GPR107 57720 Affinity Capture-MS Homo sapiens 18 B3GAT1   Proximity Label-MS Homo sapiens 19 SEC62 7095 Proximity Label-MS Homo sapiens 20 HTR4   Two-hybrid Homo sapiens 21 CREB3   Two-hybrid Homo sapiens 22 VKORC1 79001 Two-hybrid Homo sapiens 23 RPN1 6184 Proximity Label-MS Homo sapiens 24 RAB5C 5878 Proximity Label-MS Homo sapiens 25 SSR1 6745 Proximity Label-MS Homo sapiens 26 ELOVL5 60481 Proximity Label-MS Homo sapiens 27 ATP8B4   Affinity Capture-MS Homo sapiens View the network

Pathways in which TMEM230 is involved

No pathways found