Gene description for Swip-1
Gene name Swiprosin-1
Gene symbol Swip-1
Other names/aliases CG10641
DSwip-1
DmelCG10641
EFhd2
efhd
efhd2
Species Drosophila melanogaster
 Database cross references - Swip-1
ExoCarta ExoCarta_35158
Vesiclepedia VP_35158
Entrez Gene 35158
UniProt Q9VJ26  
 Swip-1 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Swip-1
Biological Process
    mesoderm development GO:0007498 IEP
Subcellular Localization
    plasma membrane GO:0005886 IDA
    muscle tendon junction GO:0005927 IDA
 Experiment description of studies that identified Swip-1 in exosomes
1
Experiment ID 202
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG10|RAB35|FLOT2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Swip-1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG1129  
Affinity Capture-MS Drosophila melanogaster
2 Plod  
Affinity Capture-MS Drosophila melanogaster
3 CG8578  
Affinity Capture-MS Drosophila melanogaster
4 Arpc3A  
Affinity Capture-MS Drosophila melanogaster
5 iotaTry  
Affinity Capture-MS Drosophila melanogaster
6 tmod  
Affinity Capture-MS Drosophila melanogaster
7 CG12177  
Affinity Capture-MS Drosophila melanogaster
8 Tm1 41852
Affinity Capture-MS Drosophila melanogaster
9 cpa 37387
Affinity Capture-MS Drosophila melanogaster
10 Arpc5  
Affinity Capture-MS Drosophila melanogaster
11 Rae1  
Affinity Capture-MS Drosophila melanogaster
12 Act57B  
Affinity Capture-MS Drosophila melanogaster
13 zip 38001
Affinity Capture-MS Drosophila melanogaster
14 CG6907  
Affinity Capture-MS Drosophila melanogaster
15 Arpc4  
Affinity Capture-MS Drosophila melanogaster
16 Cam  
Affinity Capture-MS Drosophila melanogaster
17 didum  
Affinity Capture-MS Drosophila melanogaster
18 Arp2  
Affinity Capture-MS Drosophila melanogaster
19 Arpc1  
Affinity Capture-MS Drosophila melanogaster
20 Myo61F  
Affinity Capture-MS Drosophila melanogaster
21 Arpc2  
Affinity Capture-MS Drosophila melanogaster
22 cpb 33346
Affinity Capture-MS Drosophila melanogaster
23 Rh5  
Affinity Capture-MS Drosophila melanogaster
24 CG7049  
Affinity Capture-MS Drosophila melanogaster
25 Arp3  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here