Gene description for mib2
Gene name mind bomb 2
Gene symbol mib2
Other names/aliases Be
CG17492
D-mibl
DmelCG17492
Mib-2
i115
l(2)37Be
mib1/2
suelto
Species Drosophila melanogaster
 Database cross references - mib2
ExoCarta ExoCarta_35170
Entrez Gene 35170
 mib2 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for mib2
Molecular Function
    ubiquitin-protein transferase activity GO:0004842 ISS
    zinc ion binding GO:0008270 ISM
    myosin II heavy chain binding GO:0032038 IPI
    myosin II light chain binding GO:0032033 IPI
Biological Process
    muscle cell cellular homeostasis GO:0046716 IMP
    myoblast fusion GO:0007520 IMP
    protein polyubiquitination GO:0000209 ISS
Subcellular Localization
    Z disc GO:0030018 IDA
    M band GO:0031430 IDA
    cytoplasm GO:0005737 IDA
 Experiment description of studies that identified mib2 in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for mib2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which mib2 is involved
No pathways found





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