Gene description for mib2
Gene name mind bomb 2
Gene symbol mib2
Other names/aliases Be
CG17492
D-mibl
DmelCG17492
Mib-2
i115
l(2)37Be
mib1/2
suelto
Species Drosophila melanogaster
 Database cross references - mib2
ExoCarta ExoCarta_35170
Vesiclepedia VP_35170
Entrez Gene 35170
 mib2 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for mib2
Molecular Function
    zinc ion binding GO:0008270 ISM
    myosin II light chain binding GO:0032033 IPI
    myosin II heavy chain binding GO:0032038 IPI
Biological Process
    myoblast fusion GO:0007520 IMP
    muscle cell cellular homeostasis GO:0046716 IMP
Subcellular Localization
    cytoplasm GO:0005737 IDA
    Z disc GO:0030018 IDA
    M band GO:0031430 IDA
 Experiment description of studies that identified mib2 in exosomes
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for mib2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 dos  
Affinity Capture-MS Drosophila melanogaster
2 Vps2 43164
Affinity Capture-MS Drosophila melanogaster
3 Vps4  
Affinity Capture-MS Drosophila melanogaster
4 Syb  
Affinity Capture-MS Drosophila melanogaster
5 HSPC300  
Affinity Capture-MS Drosophila melanogaster
6 chico  
Affinity Capture-MS Drosophila melanogaster
7 CG6259 39964
Affinity Capture-MS Drosophila melanogaster
8 CG18746  
Affinity Capture-MS Drosophila melanogaster
9 Dl  
Two-hybrid Drosophila melanogaster
10 CHMP2B 38599
Affinity Capture-MS Drosophila melanogaster
11 Chmp1  
Affinity Capture-MS Drosophila melanogaster
12 CG7668  
Affinity Capture-MS Drosophila melanogaster
13 CG10103 38750
Affinity Capture-MS Drosophila melanogaster
14 Flo2 32425
Affinity Capture-MS Drosophila melanogaster
15 CG10732  
Affinity Capture-MS Drosophila melanogaster
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which mib2 is involved
No pathways found





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