Gene description for CHMP2B
Gene name Charged multivesicular body protein 2b
Gene symbol CHMP2B
Other names/aliases CG4618
DmelCG4618
cg4618
Species Drosophila melanogaster
 Database cross references - CHMP2B
ExoCarta ExoCarta_38599
Entrez Gene 38599
 CHMP2B identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for CHMP2B
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    endosomal transport GO:0016197 ISS
    vacuolar transport GO:0007034 IEA
Subcellular Localization
    ESCRT III complex GO:0000815 ISS
 Experiment description of studies that identified CHMP2B in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CHMP2B
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CHMP2B is involved
No pathways found





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