Gene description for Slc25a13
Gene name solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
Gene symbol Slc25a13
Other names/aliases AI785475
Ctrn
Species Mus musculus
 Database cross references - Slc25a13
ExoCarta ExoCarta_50799
Vesiclepedia VP_50799
Entrez Gene 50799
UniProt Q9QXX4  
 Slc25a13 identified in exosomes derived from the following tissue/cell type
Melanoma cells 34957415    
Melanoma cells 34957415    
 Gene ontology annotations for Slc25a13
Molecular Function
    L-aspartate transmembrane transporter activity GO:0015183 ISO
    calcium ion binding GO:0005509 ISO
    metal ion binding GO:0046872 IEA
    L-glutamate transmembrane transporter activity GO:0005313 ISO
Biological Process
    response to calcium ion GO:0051592 ISO
    ATP biosynthetic process GO:0006754 ISO
    L-glutamate transmembrane transport GO:0089711 ISO
    cellular respiration GO:0045333 ISO
    aspartate transport GO:0015810 ISO
    transport GO:0006810 IEA
    malate-aspartate shuttle GO:0043490 ISO
    L-aspartate transmembrane transport GO:0089712 ISO
    L-glutamate transport GO:0015813 ISO
    transmembrane transport GO:0055085 IEA
Subcellular Localization
    integral component of membrane GO:0016021 IEA
    membrane GO:0016020 IEA
    mitochondrion GO:0005739 ISO
    mitochondrial inner membrane GO:0005743 TAS
 Experiment description of studies that identified Slc25a13 in exosomes
1
Experiment ID 1117
MISEV standards
EV Biophysical techniques
Cd81|Icam1
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34957415    
Organism Mus musculus
Experiment description Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H.
Journal name Nat Cancer
Publication year 2021
Sample Melanoma cells
Sample name B16-F1R2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 1118
MISEV standards
EV Biophysical techniques
Cd81|Icam1
EV Enriched markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34957415    
Organism Mus musculus
Experiment description Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H.
Journal name Nat Cancer
Publication year 2021
Sample Melanoma cells
Sample name B16-F1R2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Slc25a13
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Slc25a13 is involved
PathwayEvidenceSource
Gluconeogenesis IEA Reactome
Mitochondrial protein import IEA Reactome





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