Gene description for CDHR5
Gene name cadherin-related family member 5
Gene symbol CDHR5
Other names/aliases MU-PCDH
MUCDHL
MUPCDH
Species Homo sapiens
 Database cross references - CDHR5
ExoCarta ExoCarta_53841
Vesiclepedia VP_53841
Entrez Gene 53841
HGNC 7521
MIM 606839
UniProt Q9HBB8  
 CDHR5 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CDHR5
Molecular Function
    calcium ion binding GO:0005509 ISS
    protein binding GO:0005515 IPI
    beta-catenin binding GO:0008013 IPI
    cell adhesion molecule binding GO:0050839 IDA
Biological Process
    cell adhesion GO:0007155 IBA
    cell adhesion GO:0007155 ISS
    homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IEA
    cell differentiation GO:0030154 IEA
    regulation of microvillus length GO:0032532 IMP
    intermicrovillar adhesion GO:0090675 IMP
    brush border assembly GO:1904970 IDA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    microvillus GO:0005902 IDA
    clathrin-coated pit GO:0005905 IEA
    apical plasma membrane GO:0016324 IDA
    brush border membrane GO:0031526 IDA
    microvillus membrane GO:0031528 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified CDHR5 in exosomes
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CDHR5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SAPCD2  
Affinity Capture-MS Homo sapiens
2 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
3 UFSP2 55325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 RETSAT 54884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 LGALS1 3956
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 EFNB1 1947
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 LEMD3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 XPO7 23039
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 MBLAC2 153364
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 C1orf27 54953
Affinity Capture-MS Homo sapiens
11 SORL1 6653
Affinity Capture-MS Homo sapiens
12 FITM2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 JMJD8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CDHR5 is involved
No pathways found





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