Gene description for Caprin1
Gene name cell cycle associated protein 1
Gene symbol Caprin1
Other names/aliases AL022980
Caprin-1
Gpiap
Gpiap1
Mmgpip137
P137
rng105
Species Mus musculus
 Database cross references - Caprin1
ExoCarta ExoCarta_53872
Entrez Gene 53872
UniProt Q60865  
 Caprin1 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Caprin1
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    RNA binding GO:0003723 ISO
Biological Process
    negative regulation of translation GO:0017148 ISO
    cell differentiation GO:0030154 IEA
    positive regulation of dendrite morphogenesis GO:0050775 IMP
    positive regulation of dendritic spine morphogenesis GO:0061003 IMP
Subcellular Localization
    cell projection GO:0042995 IEA
    cytoplasmic mRNA processing body GO:0000932 ISO
    cytoplasmic stress granule GO:0010494 ISO
    cytoplasm GO:0005737 ISO
    membrane GO:0016020 ISO
 Experiment description of studies that identified Caprin1 in exosomes
1
Experiment ID 15
ISEV standards
EM
EV Biophysical techniques
EV Cytosolic markers
CD63
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Caprin1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Caprin1 is involved
No pathways found





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