Gene description for RAP1BL
Gene name
RAP1B, member of RAS oncogene family pseudogene
Gene symbol
RAP1BL
Other names/aliases
-
Species
Homo sapiens
Database cross references - RAP1BL
ExoCarta
ExoCarta_643752
Vesiclepedia
VP_643752
Entrez Gene
643752
RAP1BL identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells
17956143
Colorectal cancer cells
19837982
Urine
19056867
Gene ontology annotations for RAP1BL
Experiment description of studies that identified RAP1BL in exosomes
1
Experiment ID
20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
17956143
Organism
Homo sapiens
Experiment description
Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors
Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS
Journal name
JPR
Publication year
2007
Sample
Colorectal cancer cells
Sample name
HT29
Isolation/purification methods
Differential centrifugation Sucrose density gradient Diafiltration
Flotation density
1.16 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
2
Experiment ID
21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
PubMed ID
19837982
Organism
Homo sapiens
Experiment description
Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors
Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson
Journal name
MCP
Publication year
2009
Sample
Colorectal cancer cells
Sample name
LIM1215
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.10-1.12 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [Orbitrap] Western blotting
3
Experiment ID
63
MISEV standards
✘
Biophysical techniques
✔
AQP2
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
Protein-protein interactions for RAP1BL
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
WIF1
11197
Affinity Capture-MS
Homo sapiens
2
CD53
963
Affinity Capture-MS
Homo sapiens
3
SERBP1
26135
Affinity Capture-MS
Homo sapiens
4
TMEM257
Affinity Capture-MS
Homo sapiens
5
RPS27
6232
Affinity Capture-MS
Homo sapiens
6
CPA5
Affinity Capture-MS
Homo sapiens
7
KLRC4
Affinity Capture-MS
Homo sapiens
8
PER2
Proximity Label-MS
Homo sapiens
9
CCR1
Affinity Capture-MS
Homo sapiens
10
SCGB2A1
4246
Affinity Capture-MS
Homo sapiens
11
CERS2
29956
Affinity Capture-MS
Homo sapiens
12
MRPL42
Affinity Capture-MS
Homo sapiens
13
HBG2
3048
Affinity Capture-MS
Homo sapiens
14
KIF23
9493
Affinity Capture-MS
Homo sapiens
15
ACTL6A
86
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
16
DDX55
Affinity Capture-MS
Homo sapiens
17
DUXAP10
Affinity Capture-MS
Homo sapiens
18
DYX1C1
Affinity Capture-MS
Homo sapiens
19
SERPINB5
5268
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which RAP1BL is involved
No pathways found