Gene description for Ndufs3
Gene name NADH dehydrogenase (ubiquinone) Fe-S protein 3
Gene symbol Ndufs3
Other names/aliases 0610010M09Rik
CI-30kD
Species Mus musculus
 Database cross references - Ndufs3
ExoCarta ExoCarta_68349
Entrez Gene 68349
UniProt Q9DCT2  
 Ndufs3 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Ndufs3
Molecular Function
    oxidoreductase activity, acting on NAD(P)H GO:0016651 IEA
    NADH dehydrogenase (ubiquinone) activity GO:0008137 IEA
    oxidoreductase activity GO:0016491 IEA
    NADH dehydrogenase activity GO:0003954 ISO
Biological Process
    transport GO:0006810 IEA
    negative regulation of cell growth GO:0030308 ISO
    reactive oxygen species metabolic process GO:0072593 ISO
    negative regulation of intrinsic apoptotic signaling pathway GO:2001243 ISO
    oxidation-reduction process GO:0055114 ISO
Subcellular Localization
    nucleus GO:0005634 ISO
    mitochondrial inner membrane GO:0005743 IDA
    membrane GO:0016020 IEA
    myelin sheath GO:0043209 IDA
    mitochondrial respiratory chain complex I GO:0005747 ISO
    respiratory chain GO:0070469 IEA
    mitochondrial membrane GO:0031966 ISO
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Ndufs3 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Ndufs3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ndufs3 is involved
PathwayEvidenceSource
Respiratory electron transport IEA Reactome





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