Gene description for Ndufa8
Gene name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
Gene symbol
Ndufa8
Other names/aliases
0610033L03Rik AW261656
Species
Mus musculus
Database cross references - Ndufa8
ExoCarta
ExoCarta_68375
Vesiclepedia
VP_68375
Entrez Gene
68375
UniProt
Q9DCJ5
Ndufa8 identified in sEVs derived from the following tissue/cell type
Melanoma cells
34957415
Melanoma cells
34957415
Gene ontology annotations for Ndufa8
Experiment description of studies that identified Ndufa8 in sEVs
1
Experiment ID
1117
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
1118
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
"GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H."
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Ndufa8
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Ndufa12
Co-fractionation
Mus musculus
2
Ndufa8
68375
Cross-Linking-MS (XL-MS)
Mus musculus
Cross-Linking-MS (XL-MS)
Mus musculus
3
Kctd13
Affinity Capture-MS
Mus musculus
4
Aifm1
Cross-Linking-MS (XL-MS)
Mus musculus
5
Chchd3
Co-fractionation
Mus musculus
6
SNCA
6622
Affinity Capture-MS
Homo sapiens
7
Atp5j
Co-fractionation
Mus musculus
8
Lmo2
Two-hybrid
Mus musculus
Affinity Capture-Western
Mus musculus
9
Eed
Affinity Capture-MS
Mus musculus
10
Ndufb5
Cross-Linking-MS (XL-MS)
Mus musculus
11
Coq9
Co-fractionation
Mus musculus
12
Atp5d
Co-fractionation
Mus musculus
13
Ndufc2
Cross-Linking-MS (XL-MS)
Mus musculus
14
Htt
Affinity Capture-MS
Mus musculus
15
Cyct
Cross-Linking-MS (XL-MS)
Mus musculus
16
Slc25a4
11739
Cross-Linking-MS (XL-MS)
Mus musculus
17
Ckmt2
Cross-Linking-MS (XL-MS)
Mus musculus
18
Sucla2
Co-fractionation
Mus musculus
19
Fancd2
Affinity Capture-MS
Mus musculus
20
Cycs
13063
Cross-Linking-MS (XL-MS)
Mus musculus
21
Suclg1
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Ndufa8 is involved