Gene description for ADIPOR2
Gene name adiponectin receptor 2
Gene symbol ADIPOR2
Other names/aliases ACDCR2
PAQR2
Species Homo sapiens
 Database cross references - ADIPOR2
ExoCarta ExoCarta_79602
Entrez Gene 79602
HGNC 24041
MIM 607946
UniProt Q86V24  
 ADIPOR2 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for ADIPOR2
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    identical protein binding GO:0042802 IEA
    adiponectin binding GO:0055100 IEA
    receptor activity GO:0004872 IBA
    hormone binding GO:0042562 ISS
Biological Process
    heart development GO:0007507 IEA
    adiponectin-activated signaling pathway GO:0033211 IBA
    fatty acid oxidation GO:0019395 ISS
    hormone-mediated signaling pathway GO:0009755 ISS
    response to nutrient GO:0007584 IEA
    positive regulation of glucose import GO:0046326 IEA
    negative regulation of cell growth GO:0030308 IEA
    female pregnancy GO:0007565 IEA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified ADIPOR2 in exosomes
1
Experiment ID 226
ISEV standards
EM
EV Biophysical techniques
GAPDH
EV Cytosolic markers
CD9|FLOT1
EV Membrane markers
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for ADIPOR2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ADIPOR2 is involved
No pathways found





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