Gene description for PANK3
Gene name pantothenate kinase 3
Gene symbol PANK3
Other names/aliases -
Species Homo sapiens
 Database cross references - PANK3
ExoCarta ExoCarta_79646
Entrez Gene 79646
HGNC 19365
MIM 606161
UniProt Q9H999  
 PANK3 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for PANK3
Molecular Function
    pantothenate kinase activity GO:0004594 IEA
    ATP binding GO:0005524 IEA
Biological Process
    coenzyme A biosynthetic process GO:0015937 IEA
    phosphorylation GO:0016310 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified PANK3 in exosomes
1
Experiment ID 226
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD9|FLOT1
EV Membrane markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
✘ EV Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for PANK3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which PANK3 is involved
PathwayEvidenceSource
Coenzyme A biosynthesis TAS Reactome





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