Gene description for GRTP1
Gene name growth hormone regulated TBC protein 1
Gene symbol GRTP1
Other names/aliases TBC1D6
Species Homo sapiens
 Database cross references - GRTP1
ExoCarta ExoCarta_79774
Vesiclepedia VP_79774
Entrez Gene 79774
HGNC 20310
UniProt Q5TC63  
 GRTP1 identified in sEVs derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for GRTP1
Molecular Function
    GTPase activator activity GO:0005096 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified GRTP1 in sEVs
1
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GRTP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TBRG1  
Affinity Capture-MS Homo sapiens
2 NES 10763
Affinity Capture-MS Homo sapiens
3 FAM63A 55793
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 GJB7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 UBB 7314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 PCDHGC3 5098
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 MAGEA3  
Affinity Capture-MS Homo sapiens
8 ATP2A1 487
Affinity Capture-MS Homo sapiens
9 FBXL19  
Affinity Capture-MS Homo sapiens
10 KIF14 9928
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which GRTP1 is involved
No pathways found





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