Gene description for ZNF614
Gene name zinc finger protein 614
Gene symbol ZNF614
Other names/aliases -
Species Homo sapiens
 Database cross references - ZNF614
ExoCarta ExoCarta_80110
Vesiclepedia VP_80110
Entrez Gene 80110
HGNC 24722
UniProt Q8N883  
 ZNF614 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for ZNF614
Molecular Function
    RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000977 IBA
    DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 IBA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    regulation of transcription by RNA polymerase II GO:0006357 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified ZNF614 in exosomes
1
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for ZNF614
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC9A8 23315
Affinity Capture-MS Homo sapiens
2 NFIX 4784
Two-hybrid Homo sapiens
3 FAM9B  
Two-hybrid Homo sapiens
4 RNF2  
Affinity Capture-MS Homo sapiens
5 CUL3 8452
Affinity Capture-MS Homo sapiens
6 TRIM28 10155
Affinity Capture-MS Homo sapiens
7 DDX58 23586
Affinity Capture-RNA Homo sapiens
View the network image/svg+xml
 Pathways in which ZNF614 is involved
PathwayEvidenceSource
Gene expression (Transcription) TAS Reactome
Generic Transcription Pathway TAS Reactome
RNA Polymerase II Transcription TAS Reactome





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