Gene description for Srrt
Gene name serrate RNA effector molecule homolog (Arabidopsis)
Gene symbol Srrt
Other names/aliases 2810019G02Rik
ASR2A
ASR2B
ASR2C
ASR2D
Ars2
Asr2
Species Mus musculus
 Database cross references - Srrt
ExoCarta ExoCarta_83701
Vesiclepedia VP_83701
Entrez Gene 83701
UniProt Q99MR6  
 Srrt identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Srrt
Molecular Function
    protein binding GO:0005515 IPI
    DNA binding GO:0003677 IDA
    poly(A) RNA binding GO:0044822 ISO
Biological Process
    regulation of transcription, DNA-templated GO:0006355 IDA
    gene silencing by RNA GO:0031047 IEA
    neuronal stem cell maintenance GO:0097150 IMP
    cell proliferation GO:0008283 IMP
    primary miRNA processing GO:0031053 ISO
    transcription, DNA-templated GO:0006351 IEA
Subcellular Localization
    nucleoplasm GO:0005654 ISO
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 ISO
 Experiment description of studies that identified Srrt in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Srrt
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Srrt is involved
No pathways found





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