Gene description for FBP2
Gene name fructose-1,6-bisphosphatase 2
Gene symbol FBP2
Other names/aliases -
Species Homo sapiens
 Database cross references - FBP2
ExoCarta ExoCarta_8789
Entrez Gene 8789
HGNC 3607
MIM 603027
UniProt O00757  
 FBP2 identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for FBP2
Molecular Function
    protein binding GO:0005515 IPI
    fructose 1,6-bisphosphate 1-phosphatase activity GO:0042132 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    carbohydrate metabolic process GO:0005975 TAS
    small molecule metabolic process GO:0044281 TAS
    gluconeogenesis GO:0006094 TAS
    dephosphorylation GO:0016311 IEA
    fructose metabolic process GO:0006000 TAS
    glucose metabolic process GO:0006006 TAS
Subcellular Localization
    cell junction GO:0030054 IEA
    nucleus GO:0005634 IEA
    Z disc GO:0030018 IEA
    extracellular exosome GO:0070062 IDA
    cytosol GO:0005829 TAS
 Experiment description of studies that identified FBP2 in exosomes
1
Experiment ID 63
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✔
AQP2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for FBP2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CHD3  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which FBP2 is involved
PathwayEvidenceSource
Gluconeogenesis TAS Reactome





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