Gene description for IMMT
Gene name inner membrane protein, mitochondrial
Gene symbol IMMT
Other names/aliases HMP
MINOS2
P87
P87/89
P89
PIG4
PIG52
Species Homo sapiens
 Database cross references - IMMT
ExoCarta ExoCarta_10989
Vesiclepedia VP_10989
Entrez Gene 10989
HGNC 6047
MIM 600378
UniProt Q16891  
 IMMT identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for IMMT
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Biological Process
    inner mitochondrial membrane organization GO:0007007 IC
    cristae formation GO:0042407 IBA
    cristae formation GO:0042407 IMP
    cristae formation GO:0042407 NAS
    mitochondrial calcium ion homeostasis GO:0051560 IEA
    neuron cellular homeostasis GO:0070050 IEA
Subcellular Localization
    SAM complex GO:0001401 HDA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 IDA
    mitochondrial inner membrane GO:0005743 NAS
    mitochondrial intermembrane space GO:0005758 IEA
    membrane GO:0016020 HDA
    mitochondrial crista junction GO:0044284 NAS
    MICOS complex GO:0061617 HDA
    MICOS complex GO:0061617 IBA
    MICOS complex GO:0061617 IDA
    MICOS complex GO:0061617 IMP
    MICOS complex GO:0061617 NAS
    MIB complex GO:0140275 HDA
 Experiment description of studies that identified IMMT in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for IMMT
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 Mtx1  
Affinity Capture-MS Mus musculus
3 CHAF1A  
Cross-Linking-MS (XL-MS) Homo sapiens
4 SLC25A13 10165
Co-fractionation Homo sapiens
5 EIF2S1 1965
Cross-Linking-MS (XL-MS) Homo sapiens
6 SENP3 26168
Affinity Capture-MS Homo sapiens
7 ZNF174  
Cross-Linking-MS (XL-MS) Homo sapiens
8 CBX1 10951
Cross-Linking-MS (XL-MS) Homo sapiens
9 DNAJC11 55735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 MTCH1 23787
Proximity Label-MS Homo sapiens
11 LGR4 55366
Affinity Capture-MS Homo sapiens
12 TK1 7083
Two-hybrid Homo sapiens
13 Mtx2  
Affinity Capture-MS Mus musculus
14 VAPA 9218
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
15 FBXL4 26235
Affinity Capture-MS Homo sapiens
16 SAMM50 25813
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
17 CCDC113  
Two-hybrid Homo sapiens
18 CLEC5A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 STMN4  
Two-hybrid Homo sapiens
20 LRIF1  
Two-hybrid Homo sapiens
21 ADRB2  
Affinity Capture-MS Homo sapiens
22 FASTKD5  
Proximity Label-MS Homo sapiens
23 CRY1  
Affinity Capture-MS Homo sapiens
24 SPSB4  
Affinity Capture-MS Homo sapiens
25 KIF20A 10112
Affinity Capture-MS Homo sapiens
26 MGARP  
Affinity Capture-MS Homo sapiens
27 SLC25A1 6576
Co-fractionation Homo sapiens
28 DNAJC25 548645
Proximity Label-MS Homo sapiens
29 CALM1 801
Reconstituted Complex Homo sapiens
30 DHX57 90957
Cross-Linking-MS (XL-MS) Homo sapiens
31 HNRNPR 10236
Co-fractionation Homo sapiens
32 NDUFA4 4697
Affinity Capture-MS Homo sapiens
33 PTPN1 5770
Proximity Label-MS Homo sapiens
34 Actb 11461
Affinity Capture-MS Mus musculus
35 C15orf48  
Affinity Capture-MS Homo sapiens
36 FFAR1  
Affinity Capture-MS Homo sapiens
37 NDUFS2 4720
Co-fractionation Homo sapiens
38 FAXC  
Affinity Capture-MS Homo sapiens
39 CCDC90B  
Proximity Label-MS Homo sapiens
40 TMPO 7112
Affinity Capture-MS Homo sapiens
41 TOMM22 56993
Co-fractionation Homo sapiens
42 ABCD1 215
Co-fractionation Homo sapiens
43 USP36  
Affinity Capture-MS Homo sapiens
44 KIAA1429 25962
Affinity Capture-MS Homo sapiens
45 SLC18A2  
Affinity Capture-MS Homo sapiens
46 MARCH5  
Proximity Label-MS Homo sapiens
47 NDUFB9 4715
Two-hybrid Homo sapiens
48 TBL2 26608
Co-fractionation Homo sapiens
49 FIS1 51024
Proximity Label-MS Homo sapiens
50 SLC15A1  
Affinity Capture-MS Homo sapiens
51 NDUFS3 4722
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
52 DTX3  
Affinity Capture-MS Homo sapiens
53 FAM173A  
Two-hybrid Homo sapiens
54 KIF22  
Two-hybrid Homo sapiens
55 TGFB1 7040
Affinity Capture-MS Homo sapiens
56 KIF23 9493
Affinity Capture-MS Homo sapiens
57 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 CAMSAP3  
Cross-Linking-MS (XL-MS) Homo sapiens
59 PTPMT1 114971
Affinity Capture-MS Homo sapiens
60 PRC1 9055
Affinity Capture-MS Homo sapiens
61 CHCHD10  
Affinity Capture-MS Homo sapiens
62 MDC1  
Affinity Capture-MS Homo sapiens
63 DDRGK1 65992
Affinity Capture-MS Homo sapiens
64 ASB9  
Affinity Capture-MS Homo sapiens
65 ARMCX3 51566
Two-hybrid Homo sapiens
66 RER1 11079
Two-hybrid Homo sapiens
67 BOD1L1 259282
Cross-Linking-MS (XL-MS) Homo sapiens
68 DNAJB1 3337
Proximity Label-MS Homo sapiens
69 ABCE1 6059
Affinity Capture-MS Homo sapiens
70 SURF1  
Proximity Label-MS Homo sapiens
71 SLC2A8 29988
Affinity Capture-MS Homo sapiens
72 CLPB 81570
Proximity Label-MS Homo sapiens
73 FANCD2  
Affinity Capture-MS Homo sapiens
74 EXD2  
Proximity Label-MS Homo sapiens
75 ITGA4 3676
Affinity Capture-MS Homo sapiens
76 VDAC1 7416
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
77 SLC25A46 91137
Proximity Label-MS Homo sapiens
78 NDUFV1 4723
Co-fractionation Homo sapiens
79 VCAM1 7412
Affinity Capture-MS Homo sapiens
80 TOMM40 10452
Affinity Capture-MS Homo sapiens
81 SPRTN  
Affinity Capture-MS Homo sapiens
82 CALR 811
Co-fractionation Homo sapiens
83 RNF126  
Affinity Capture-MS Homo sapiens
84 CHCHD6 84303
Affinity Capture-Western Homo sapiens
85 AKTIP  
Two-hybrid Homo sapiens
86 CHD3 1107
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
87 UBQLN4 56893
Two-hybrid Homo sapiens
88 FGFR1 2260
Affinity Capture-MS Homo sapiens
89 UQCRQ 27089
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
90 NCSTN 23385
Affinity Capture-MS Homo sapiens
91 OBSL1 23363
Affinity Capture-MS Homo sapiens
92 KIF14 9928
Affinity Capture-MS Homo sapiens
93 ESR1  
Affinity Capture-MS Homo sapiens
94 P2RY8  
Affinity Capture-MS Homo sapiens
95 APOO 79135
Proximity Label-MS Homo sapiens
96 BAG5 9529
Affinity Capture-MS Homo sapiens
97 LRRC59 55379
Co-fractionation Homo sapiens
98 PCNP 57092
Affinity Capture-MS Homo sapiens
99 ATP5A1 498
Affinity Capture-MS Homo sapiens
100 DBNL 28988
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
101 COX15 1355
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
102 NEB 4703
Cross-Linking-MS (XL-MS) Homo sapiens
103 DIABLO 56616
Proximity Label-MS Homo sapiens
104 IRAK1  
Affinity Capture-MS Homo sapiens
105 NCKIPSD 51517
Proximity Label-MS Homo sapiens
106 TSFM 10102
Proximity Label-MS Homo sapiens
107 ECT2 1894
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 PARK2  
Affinity Capture-MS Homo sapiens
109 ALB 213
Two-hybrid Homo sapiens
110 PIAS4  
Two-hybrid Homo sapiens
111 CSTF2 1478
Two-hybrid Homo sapiens
112 HSP90B1 7184
Co-fractionation Homo sapiens
113 CCT5 22948
Two-hybrid Homo sapiens
114 BAG6 7917
Two-hybrid Homo sapiens
115 ATF2  
Affinity Capture-MS Homo sapiens
116 SRRT 51593
Two-hybrid Homo sapiens
117 ATG16L1 55054
Affinity Capture-MS Homo sapiens
118 KDSR 2531
Affinity Capture-MS Homo sapiens
119 DNAJC5 80331
Proximity Label-MS Homo sapiens
120 NDUFS8 4728
Co-fractionation Homo sapiens
121 CHMP4B 128866
Affinity Capture-MS Homo sapiens
122 Klhl21  
Affinity Capture-MS Mus musculus
123 MYH9 4627
Affinity Capture-MS Homo sapiens
124 VCP 7415
Affinity Capture-MS Homo sapiens
125 B3GNT2 10678
Affinity Capture-MS Homo sapiens
126 NTRK1 4914
Affinity Capture-MS Homo sapiens
127 HMOX2 3163
Two-hybrid Homo sapiens
128 CCDC109B 55013
Proximity Label-MS Homo sapiens
129 OPA1 4976
Proximity Label-MS Homo sapiens
130 EXOC6 54536
Affinity Capture-MS Homo sapiens
131 LAMP1 3916
Proximity Label-MS Homo sapiens
132 ASCC2 84164
Two-hybrid Homo sapiens
133 CYC1 1537
Co-fractionation Homo sapiens
134 HJURP  
Two-hybrid Homo sapiens
135 ENO1 2023
Cross-Linking-MS (XL-MS) Homo sapiens
136 LACTB 114294
Co-fractionation Homo sapiens
137 PLA2G15 23659
Two-hybrid Homo sapiens
138 STX5 6811
Two-hybrid Homo sapiens
139 NCAPD2 9918
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
140 MAGEA8  
Affinity Capture-MS Homo sapiens
141 DNAJC30  
Proximity Label-MS Homo sapiens
142 RHOT2 89941
Proximity Label-MS Homo sapiens
143 VDAC2 7417
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
144 ARMCX2 9823
Co-fractionation Homo sapiens
145 HAP1  
Two-hybrid Homo sapiens
146 SLC33A1 9197
Affinity Capture-MS Homo sapiens
147 ADCK5  
Affinity Capture-MS Homo sapiens
148 RMDN3 55177
Proximity Label-MS Homo sapiens
149 COX4I1 1327
Proximity Label-MS Homo sapiens
150 ANLN 54443
Affinity Capture-MS Homo sapiens
151 ATXN1 6310
Two-hybrid Homo sapiens
152 DST 667
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
153 DISC1 27185
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Two-hybrid Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
154 HNRNPD 3184
Two-hybrid Homo sapiens
155 Rab5c 19345
Affinity Capture-MS Mus musculus
156 MRPL44  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
157 SFPQ 6421
Co-fractionation Homo sapiens
158 KPNA2 3838
Two-hybrid Homo sapiens
159 ZBTB2 57621
Affinity Capture-MS Homo sapiens
160 SGPL1 8879
Co-fractionation Homo sapiens
161 SLC2A1 6513
Affinity Capture-MS Homo sapiens
162 CLN3 1201
Affinity Capture-MS Homo sapiens
163 SEPT10 151011
Cross-Linking-MS (XL-MS) Homo sapiens
164 HADHB 3032
Co-fractionation Homo sapiens
165 SLC25A12 8604
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
166 MINOS1  
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
167 AIFM1 9131
Proximity Label-MS Homo sapiens
168 RAB7A 7879
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
169 VPS36 51028
Cross-Linking-MS (XL-MS) Homo sapiens
170 AMBRA1  
Affinity Capture-MS Homo sapiens
171 C9orf78 51759
Affinity Capture-MS Homo sapiens
172 NDUFA9 4704
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
173 SLC25A51  
Proximity Label-MS Homo sapiens
174 MSMO1 6307
Co-fractionation Homo sapiens
175 CLPP 8192
Proximity Label-MS Homo sapiens
176 SIRT7  
Affinity Capture-MS Homo sapiens
177 MTX2 10651
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
178 NOS3  
Two-hybrid Homo sapiens
179 UQCRC2 7385
Co-fractionation Homo sapiens
180 TRAF3IP1 26146
Two-hybrid Homo sapiens
181 CTNNB1 1499
Affinity Capture-MS Homo sapiens
182 PTH2R  
Affinity Capture-MS Homo sapiens
183 Bmpr1a  
Affinity Capture-MS Mus musculus
184 GOLT1B 51026
Affinity Capture-MS Homo sapiens
185 Rmdn3  
Affinity Capture-MS Mus musculus
186 PRKCZ 5590
Affinity Capture-MS Homo sapiens
187 COX7A2 1347
Co-fractionation Homo sapiens
188 RMND1 55005
Proximity Label-MS Homo sapiens
189 EGFR 1956
Affinity Capture-MS Homo sapiens
190 FKBP8 23770
Proximity Label-MS Homo sapiens
191 MYO19  
Affinity Capture-MS Homo sapiens
192 FBXO6 26270
Affinity Capture-MS Homo sapiens
193 DHX30 22907
Proximity Label-MS Homo sapiens
194 ANKRD11 29123
Cross-Linking-MS (XL-MS) Homo sapiens
195 TRAK2 66008
Affinity Capture-MS Homo sapiens
196 SUZ12  
Affinity Capture-MS Homo sapiens
197 TXNDC9 10190
Two-hybrid Homo sapiens
198 C17orf80 55028
Proximity Label-MS Homo sapiens
199 ATP5B 506
Co-fractionation Homo sapiens
200 HADHA 3030
Co-fractionation Homo sapiens
201 PRKACA 5566
Affinity Capture-MS Homo sapiens
202 CAMSAP2  
Cross-Linking-MS (XL-MS) Homo sapiens
203 RPUSD4 84881
Proximity Label-MS Homo sapiens
204 APOOL 139322
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 DLST 1743
Affinity Capture-MS Homo sapiens
206 C19orf70  
Affinity Capture-MS Homo sapiens
207 UQCRC1 7384
Co-fractionation Homo sapiens
208 CD244 51744
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 HP1BP3 50809
Co-fractionation Homo sapiens
210 ENO2 2026
Cross-Linking-MS (XL-MS) Homo sapiens
211 SMN1 6606
Two-hybrid Homo sapiens
212 BMI1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
213 NDUFA10 4705
Co-fractionation Homo sapiens
214 KRAS 3845
Negative Genetic Homo sapiens
215 NUP35 129401
Proximity Label-MS Homo sapiens
216 RNF26  
Affinity Capture-MS Homo sapiens
217 LRRN4CL 221091
Affinity Capture-MS Homo sapiens
218 MTM1 4534
Affinity Capture-MS Homo sapiens
219 BRD3 8019
Cross-Linking-MS (XL-MS) Homo sapiens
220 NDUFS1 4719
Co-fractionation Homo sapiens
221 AKAP1 8165
Proximity Label-MS Homo sapiens
222 MCUR1 63933
Proximity Label-MS Homo sapiens
223 CCDC8  
Affinity Capture-MS Homo sapiens
224 TNNT1  
Two-hybrid Homo sapiens
225 EEF1A1 1915
Two-hybrid Homo sapiens
226 IMMT 10989
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
227 SDHAF2 54949
Two-hybrid Homo sapiens
228 NIPSNAP3A  
Two-hybrid Homo sapiens
229 DNAJC4  
Proximity Label-MS Homo sapiens
230 EXOSC10 5394
Two-hybrid Homo sapiens
231 FEZ1  
Two-hybrid Homo sapiens
232 EIF3F 8665
Affinity Capture-MS Homo sapiens
233 C8orf33 65265
Two-hybrid Homo sapiens
234 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
235 PHB2 11331
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
236 OCIAD1 54940
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
237 PRRC2A 7916
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
238 AUH 549
Proximity Label-MS Homo sapiens
239 PARP1 142
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
240 PDE4B  
Protein-RNA Homo sapiens
241 TRAK1 22906
Affinity Capture-MS Homo sapiens
242 DNAJC19 131118
Proximity Label-MS Homo sapiens
243 CHCHD3 54927
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
244 ICT1 3396
Affinity Capture-MS Homo sapiens
245 MFSD4  
Affinity Capture-MS Homo sapiens
246 UBE2L6 9246
Affinity Capture-MS Homo sapiens
247 LONP1 9361
Proximity Label-MS Homo sapiens
248 Aifm1  
Affinity Capture-MS Mus musculus
249 COX7C 1350
Co-fractionation Homo sapiens
250 ISG15 9636
Affinity Capture-MS Homo sapiens
251 CDC37 11140
Two-hybrid Homo sapiens
252 TUBGCP3 10426
Two-hybrid Homo sapiens
253 PFDN1 5201
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
254 PDHA1 5160
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
255 DNAJA3 9093
Proximity Label-MS Homo sapiens
256 Ckap5 75786
Affinity Capture-MS Mus musculus
257 SQSTM1 8878
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
258 PPOX 5498
Two-hybrid Homo sapiens
259 NDUFA12 55967
Affinity Capture-MS Homo sapiens
260 PDHB 5162
Co-fractionation Homo sapiens
261 CAPZB 832
Affinity Capture-MS Homo sapiens
262 SNAPIN 23557
Two-hybrid Homo sapiens
263 OTUB1 55611
Affinity Capture-MS Homo sapiens
264 TAF1D  
Two-hybrid Homo sapiens
265 C21orf33  
Proximity Label-MS Homo sapiens
266 KLF16  
Affinity Capture-MS Homo sapiens
267 MMGT1 93380
Affinity Capture-MS Homo sapiens
268 SFXN1 94081
Proximity Label-MS Homo sapiens
269 TMEM70  
Proximity Label-MS Homo sapiens
270 UFL1 23376
Affinity Capture-MS Homo sapiens
271 Samm50  
Affinity Capture-MS Mus musculus
272 C10orf88  
Two-hybrid Homo sapiens
273 KDM1A 23028
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
274 NEK2  
Two-hybrid Homo sapiens
275 PDE2A  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
276 EZH2  
Affinity Capture-MS Homo sapiens
277 SRCAP  
Cross-Linking-MS (XL-MS) Homo sapiens
278 ADCK1  
Affinity Capture-MS Homo sapiens
279 CDK9 1025
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
280 PINK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
281 TCF3  
Affinity Capture-MS Homo sapiens
282 ACO2 50
Affinity Capture-MS Homo sapiens
283 NDEL1 81565
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Far Western Homo sapiens
284 MCU 90550
Proximity Label-MS Homo sapiens
285 SERBP1 26135
Affinity Capture-MS Homo sapiens
286 PDE4DIP 9659
Two-hybrid Homo sapiens
287 CUL7 9820
Affinity Capture-MS Homo sapiens
288 ATP5C1 509
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
289 RAB5C 5878
Affinity Capture-MS Homo sapiens
290 C9orf72  
Affinity Capture-MS Homo sapiens
291 WFS1 7466
Co-fractionation Homo sapiens
292 VDAC3 7419
Co-fractionation Homo sapiens
293 HIVEP1 3096
Two-hybrid Homo sapiens
294 C19orf52  
Proximity Label-MS Homo sapiens
295 BCKDHA 593
Co-fractionation Homo sapiens
296 TOMM5  
Co-fractionation Homo sapiens
297 FBXL6  
Affinity Capture-MS Homo sapiens
298 EP300 2033
Two-hybrid Homo sapiens
299 ECSIT 51295
Two-hybrid Homo sapiens
300 MTCH2 23788
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IMMT is involved
PathwayEvidenceSource
Cristae formation IEA Reactome
Mitochondrial biogenesis IEA Reactome
Organelle biogenesis and maintenance IEA Reactome





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