Gene description for Col5a1
Gene name collagen, type V, alpha 1
Gene symbol Col5a1
Other names/aliases AI413331
Species Mus musculus
 Database cross references - Col5a1
ExoCarta ExoCarta_12831
Entrez Gene 12831
UniProt O88207  
 Col5a1 identified in exosomes derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Col5a1
Molecular Function
    heparin binding GO:0008201 ISO
    protein binding GO:0005515 IPI
    proteoglycan binding GO:0043394 ISO
    platelet-derived growth factor binding GO:0048407 ISO
    extracellular matrix structural constituent GO:0005201 IDA
Biological Process
    regulation of cellular component organization GO:0051128 IMP
    skin development GO:0043588 ISO
    extracellular fibril organization GO:0043206 ISO
    tendon development GO:0035989 IMP
    negative regulation of endodermal cell differentiation GO:1903225 ISO
    eye morphogenesis GO:0048592 ISO
    integrin biosynthetic process GO:0045112 ISO
    collagen fibril organization GO:0030199 ISO
    heart morphogenesis GO:0003007 IGI
    cell migration GO:0016477 ISO
    cell adhesion GO:0007155 ISO
    collagen biosynthetic process GO:0032964 ISO
    blood vessel development GO:0001568 IMP
    wound healing, spreading of epidermal cells GO:0035313 ISO
Subcellular Localization
    proteinaceous extracellular matrix GO:0005578 IDA
    extracellular exosome GO:0070062 ISO
    collagen type V trimer GO:0005588 ISO
    extracellular region GO:0005576 IEA
    extracellular matrix GO:0031012 ISO
    collagen trimer GO:0005581 IMP
    basement membrane GO:0005604 IDA
 Experiment description of studies that identified Col5a1 in exosomes
Experiment ID 210
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL.
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Col5a1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.

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