Gene description for Hgs
Gene name	HGF-regulated tyrosine kinase substrate
Gene symbol	Hgs
Other names/aliases	Hgr Hrs ZFYVE8
Species	Mus musculus
Database cross references - Hgs
ExoCarta	ExoCarta_15239
Vesiclepedia	VP_15239
Entrez Gene	15239
UniProt	Q99LI8
Hgs identified in exosomes derived from the following tissue/cell type
Melanoma cells	30089911

Gene ontology annotations for Hgs

Molecular Function     protein binding GO:0005515 IPI     protein domain specific binding GO:0019904 ISO     phosphatidylinositol binding GO:0035091 IEA     identical protein binding GO:0042802 IPI     ubiquitin binding GO:0043130 IBA     ubiquitin binding GO:0043130 IEA     ubiquitin-like protein ligase binding GO:0044389 ISO     metal ion binding GO:0046872 IEA     ubiquitin-modified protein reader activity GO:0140036 IDA Biological Process     protein targeting to lysosome GO:0006622 ISO     endosome to lysosome transport GO:0008333 ISO     membrane invagination GO:0010324 ISO     positive regulation of gene expression GO:0010628 ISO     negative regulation of platelet-derived growth factor receptor signaling pathway GO:0010642 ISO     protein transport GO:0015031 IEA     negative regulation of angiogenesis GO:0016525 ISO     negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948 ISO     receptor internalization GO:0031623 IBA     endocytic recycling GO:0032456 IBA     regulation of MAP kinase activity GO:0043405 ISO     negative regulation of receptor signaling pathway via JAK-STAT GO:0046426 ISO     protein localization to membrane GO:0072657 ISO     positive regulation of exosomal secretion GO:1903543 ISO Subcellular Localization     cytoplasm GO:0005737 IDA     lysosome GO:0005764 ISO     endosome GO:0005768 ISO     early endosome GO:0005769 IBA     early endosome GO:0005769 ISO     cytosol GO:0005829 ISO     secretory granule GO:0030141 ISO     early endosome membrane GO:0031901 IEA     multivesicular body membrane GO:0032585 IEA     ESCRT-0 complex GO:0033565 ISO