Gene description for EPO
Gene name	erythropoietin
Gene symbol	EPO
Other names/aliases	EP MVCD2
Species	Homo sapiens
Database cross references - EPO
ExoCarta	ExoCarta_2056
Entrez Gene	2056
HGNC	3415
MIM	133170
UniProt	P01588
EPO identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for EPO

Molecular Function     protein binding GO:0005515 IPI     erythropoietin receptor binding GO:0005128 IEA     hormone activity GO:0005179 IEA     protein kinase activator activity GO:0030295 IEA Biological Process     embryo implantation GO:0007566 IEA     response to hyperoxia GO:0055093 IEA     cellular hyperosmotic response GO:0071474 IDA     response to testosterone GO:0033574 IEA     positive regulation of protein kinase activity GO:0045860 IEA     cellular response to hypoxia GO:0071456 TAS     response to interleukin-1 GO:0070555 IEA     regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061418 TAS     positive regulation of transcription, DNA-templated GO:0045893 IDA     signal transduction GO:0007165 NAS     negative regulation of cation channel activity GO:2001258 IDA     aging GO:0007568 IEA     negative regulation of calcium ion transport into cytosol GO:0010523 IDA     positive regulation of neuron differentiation GO:0045666 IEA     positive regulation of DNA replication GO:0045740 IDA     blood circulation GO:0008015 NAS     negative regulation of erythrocyte apoptotic process GO:1902251 IDA     apoptotic process GO:0006915 IEA     positive regulation of Ras protein signal transduction GO:0046579 IDA     peptidyl-serine phosphorylation GO:0018105 IEA     response to estrogen GO:0043627 IEA     response to lipopolysaccharide GO:0032496 IEA     negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902219 IDA     erythrocyte maturation GO:0043249 IEA     positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 IDA     response to electrical stimulus GO:0051602 IEA     positive regulation of cell proliferation GO:0008284 IDA     hemoglobin biosynthetic process GO:0042541 IEA     response to vitamin A GO:0033189 IEA     response to axon injury GO:0048678 IEA     response to salt stress GO:0009651 IEA Subcellular Localization     extracellular space GO:0005615 IDA     cell surface GO:0009986 IDA     extracellular region GO:0005576 TAS