Gene description for KCTD20
Gene name potassium channel tetramerization domain containing 20
Gene symbol KCTD20
Other names/aliases C6orf69
Species Homo sapiens
 Database cross references - KCTD20
ExoCarta ExoCarta_222658
Entrez Gene 222658
HGNC 21052
MIM 615932
UniProt Q7Z5Y7  
 KCTD20 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for KCTD20
Biological Process
    positive regulation of phosphorylation GO:0042327 ISS
    protein homooligomerization GO:0051260 IEA
Subcellular Localization
    cytoplasm GO:0005737 ISS
 Experiment description of studies that identified KCTD20 in exosomes
Experiment ID 235
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for KCTD20
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KCTD20 is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here